26 July 2020: Clinical Research
Is Noninvasive Prenatal Screening Appropriate for Pregnant Women Age 35 or Older In Cases if Isolated Fetal Nasal Bone Abnormalities in The Chinese Han Population?
Yuan Chen 1ACDEF* , Min Lv 1ABEF* , Tian Dong 1BC , Qinqing Chen 1BC , Yeqing Qian 2AD , Baihui Zhao 1ADFG , Qiong Luo 1ADEFG*DOI: 10.12659/MSM.924387
Med Sci Monit 2020; 26:e924387
Table 1 Characteristic of cases with fetal nasal bone absence or hypoplasia.
| Variable | Result (median/mean±SD) | Range | |
|---|---|---|---|
| Age (years) | 31 | 21–48 | |
| CRL (mm) | 68 | 37–86 | |
| NT (mm) | 1.5±0.8 | ||
| Gravidity (n) | 2 | 1–10 | |
| Parity (n) | 0 | 0–4 | |
| TOP (n) | 77 | ||
| Chromosome abnormality | 60 | ||
| Non-chromosome abnormality | 13 | ||
| Other reasons | 4 | ||
| Miscarriage (n) | 23 | ||
| Birth (n) | 1746 | ||
| Birth weight(g) | 3309±429 | ||
| Gestational weeks at delivery | 39 | 28–41 | |
| TOP – termination of pregnancy; other reasons for TOP – pregnancy complications such as preeclampsia, pregnant with mental disease or mother’s unwillingness to proceed pregnancy. | |||