26 July 2020 : Clinical Research
Is Noninvasive Prenatal Screening Appropriate for Pregnant Women Age 35 or Older In Cases if Isolated Fetal Nasal Bone Abnormalities in The Chinese Han Population?
Yuan Chen1ACDEF, Min Lv1ABEF, Tian Dong1BC, Qinqing Chen1BC, Yeqing Qian2AD, Baihui Zhao1ADFG, Qiong Luo1ADEFG*DOI: 10.12659/MSM.924387
Med Sci Monit 2020; 26:e924387
Table 1 Characteristic of cases with fetal nasal bone absence or hypoplasia.
| Variable | Result (median/mean±SD) | Range | |
|---|---|---|---|
| Age (years) | 31 | 21–48 | |
| CRL (mm) | 68 | 37–86 | |
| NT (mm) | 1.5±0.8 | ||
| Gravidity (n) | 2 | 1–10 | |
| Parity (n) | 0 | 0–4 | |
| TOP (n) | 77 | ||
| Chromosome abnormality | 60 | ||
| Non-chromosome abnormality | 13 | ||
| Other reasons | 4 | ||
| Miscarriage (n) | 23 | ||
| Birth (n) | 1746 | ||
| Birth weight(g) | 3309±429 | ||
| Gestational weeks at delivery | 39 | 28–41 | |
| TOP – termination of pregnancy; other reasons for TOP – pregnancy complications such as preeclampsia, pregnant with mental disease or mother’s unwillingness to proceed pregnancy. | |||