26 July 2020 : Clinical Research
Is Noninvasive Prenatal Screening Appropriate for Pregnant Women Age 35 or Older In Cases if Isolated Fetal Nasal Bone Abnormalities in The Chinese Han Population?
Yuan Chen1ACDEF, Min Lv1ABEF, Tian Dong1BC, Qinqing Chen1BC, Yeqing Qian2AD, Baihui Zhao1ADFG, Qiong Luo1ADEFG*DOI: 10.12659/MSM.924387
Med Sci Monit 2020; 26:e924387
Table 2 Evaluation of NIPS and conventional maternal serum screening in nasal bone abnormality population.
| TP | FP | TN | FN | Sensitivity | Specificity | PPV | NPV | |
|---|---|---|---|---|---|---|---|---|
| CMSS | 1 | 68 | 1162 | 5 | 17% | 94.47% | 1.45% | 99.57% |
| NIPS | 5 | 0 | 424 | 0 | 100% | 100.00% | 100.00% | 100.00% |
| TP – true positive; FP – false positive; FN – false negative; TN – true negative; PPV – positive predictive value; NPV – negative predictive value; NIPS – non-invasive prenatal screening; CMSS – conventional maternal serum screening. | ||||||||