26 July 2020>: Clinical Research
Is Noninvasive Prenatal Screening Appropriate for Pregnant Women Age 35 or Older In Cases if Isolated Fetal Nasal Bone Abnormalities in The Chinese Han Population?
Yuan Chen 1ACDEF* , Min Lv 1ABEF* , Tian Dong 1BC , Qinqing Chen 1BC , Yeqing Qian 2AD , Baihui Zhao 1ADFG , Qiong Luo 1ADEFG*DOI: 10.12659/MSM.924387
Med Sci Monit 2020; 26:e924387
Table 2 Evaluation of NIPS and conventional maternal serum screening in nasal bone abnormality population.
TP | FP | TN | FN | Sensitivity | Specificity | PPV | NPV | |
---|---|---|---|---|---|---|---|---|
CMSS | 1 | 68 | 1162 | 5 | 17% | 94.47% | 1.45% | 99.57% |
NIPS | 5 | 0 | 424 | 0 | 100% | 100.00% | 100.00% | 100.00% |
TP – true positive; FP – false positive; FN – false negative; TN – true negative; PPV – positive predictive value; NPV – negative predictive value; NIPS – non-invasive prenatal screening; CMSS – conventional maternal serum screening. |