30 July 2020 : Clinical Research
Fiber Type-Specific Morphological and Cellular Changes of Paraspinal Muscles in Patients with Severe Adolescent Idiopathic Scoliosis
Xiexiang Shao1ABCEF, Jian Chen1ABCF, Jingfan Yang1ADFG, Wenyuan Sui1BDFG, Yaolong Deng1BCEF, Zifang Huang2BCE, Ping Hu3ACEG, Junlin Yang1ABCDEG*DOI: 10.12659/MSM.924415
Med Sci Monit 2020; 26:e924415
Table 4 Correlation analysis between clinical parameters and the bilateral differences of fiber type specific morphological/cellular characteristics.
Age at initiation | Cobb angle | AVT | CB | |||||
---|---|---|---|---|---|---|---|---|
r | P value | r | P value | r | P value | r | P value | |
Difference of type I numerical proportion | −0.120 | 0.711 | −0.002 | 0.996 | −0.494 | 0.103 | −0.167 | 0.603 |
Difference of type I area proportion | −0.198 | 0.537 | −0.061 | 0.850 | −0.182 | 0.571 | 0.091 | 0.779 |
Ratio of CSA | ||||||||
Type I | 0.004 | 0.991 | * | 0.497 | 0.100 | 0.040 | 0.901 | |
Type II | −0.172 | 0.593 | * | 0.322 | 0.307 | −0.269 | 0.398 | |
Total | 0.007 | 0.982 | * | 0.438 | 0.155 | −0.180 | 0.576 | |
Difference of myonuclei density | ||||||||
Type I | −0.071 | 0.826 | 0.302 | 0.341 | * | −0.150 | 0.641 | |
Type II | 0.108 | 0.737 | −0.175 | 0.587 | −0.133 | 0.680 | −0.329 | 0.297 |
Total | 0.093 | 0.773 | 0.326 | 0.301 | 0.571 | 0.053 | −0.349 | 0.266 |
Difference of total SC density | ||||||||
Type I | −0.228 | 0.476 | 0.351 | 0.263 | * | 0.465 | 0.127 | |
Type II | 0.150 | 0.643 | 0.266 | 0.403 | * | 0.088 | 0.787 | |
Total | −0.019 | 0.954 | 0.346 | 0.271 | 0.539 | 0.070 | 0.328 | 0.297 |
Difference of activated SC density | ||||||||
Type I | −0.116 | 0.720 | 0.495 | 0.102 | * | 0.053 | 0.870 | |
Type II | 0.225 | 0.482 | 0.269 | 0.399 | −0.025 | 0.940 | −0.523 | 0.081 |
Total | −0.064 | 0.844 | 0.575 | 0.050 | 0.392 | 0.207 | −0.427 | 0.166 |
AVT – apical vertebrae translation; CB – coronal balance; CSA – cross sectional area; SC – satellite cell. * Significant if value |