Extracellular Vesicle-Transported Long Non-Coding RNA (LncRNA) X Inactive-Specific Transcript (XIST) in Serum is a Potential Novel Biomarker for Colorectal Cancer Diagnosis

Jinfeng Yu; Weiwei Dong; Jianxiao Liang

doi:10.12659/MSM.924448

15 August 2020 : Clinical Research

Extracellular Vesicle-Transported Long Non-Coding RNA (LncRNA) X Inactive-Specific Transcript (XIST) in Serum is a Potential Novel Biomarker for Colorectal Cancer Diagnosis

Jinfeng Yu^1ABE, Weiwei Dong^2FG, Jianxiao Liang^3CD*

DOI: 10.12659/MSM.924448

Med Sci Monit 2020; 26:e924448

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Supplementary Table 1 Demographic characteristics of the CRC patients.

No.	Type	Stage	M	D	TS	Gender	Age	OS (months)	Status
1	CRC	I	Y	High		Male	66	18	Dead
2	CRC	II	N	Medium		Female	51	24	Dead
3	CRC	III	Y	Low	>3 cm	Male	63	36	Dead
4	CRC	IV	Y	Low		Male	38	60	Live
5	CRC	II	N	High		Male	60	60	Live
6	CRC	IV	Y	Low		Female	53	30	Dead
7	CRC	IV	N	Low		Female	68	42	Dead
8	CRC	II	Y	Low		Male	52	39	Dead
9	CRC	IV	N	Low		Male	56	18	Dead
10	CRC	IV	Y	High		Female	62	12	Dead
11	CRC	IV	Y	Low	>3 cm	Female	66	18	Dead
12	CRC	IV	Y	Low		Male	71	15	Dead
13	CRC	IV	Y	High	>3 cm	Male	61	36	Dead
14	CRC	IV	N	Low	>3 cm	Male	71	42	Live
15	CRC	IV	Y	Low		Female	67	30	Dead
16	CRC	III	Y	Low		Female	66	39	Dead
17	CRC	IV	N	Medium		Male	66	33	Dead
18	CRC	IV	Y	Medium		Male	71	36	Dead
19	CRC	IV	Y	Low	>3 cm	Male	58	45	Live
20	CRC	III	Y	Low		Female	64	30	Dead
21	CRC	IV	Y	Medium	>3 cm	Female	58	15	Dead
22	CRC	IV	Y	Medium		Female	63	18	Dead
23	CRC	IV	N	Low	>3 cm	Female	72	33	Dead
24	CRC	I	Y	Low	>3 cm	Female	65	36	Dead
25	CRC	IV	N	Low		Male	60	60	Live
26	CRC	IV	Y	Medium	>3 cm	Male	60	24	Dead
27	CRC	IV	N	Medium		Male	61	24	Dead
28	CRC	III	Y	Medium	>3 cm	Female	66	33	Dead
29	CRC	III	N	Medium	>3 cm	Male	71	39	Dead
30	CRC	II	Y	Medium		Female	58	24	Dead
31	CRC	III	Y	Low	>3 cm	Male	66	60	Live
32	CRC	III	N	Low		Female	66	27	Dead
33	CRC	IV	Y	Low	>3 cm	Female	65	39	Dead
34	CRC	IV	Y	Low	>3 cm	Female	64	36	Dead
35	CRC	III	N	Medium		Male	73	39	Dead
36	CRC	III	Y	Medium	>3 cm	Female	73	27	Dead
37	CRC	III	Y	Medium		Female	66	45	Dead
38	CRC	III	Y	Low	>3 cm	Male	68	54	Dead
39	CRC	III	N	Medium	>3 cm	Female	67	30	Dead
40	CRC	III	Y	Medium		Male	63	60	Live
41	CRC	III	Y	Medium		Female	61	36	Dead
42	CRC	III	Y	Low	>3 cm	Male	67	18	Dead
43	CRC	III	N	Medium	>3 cm	Female	68	15	Dead
44	CRC	II	Y	Medium		Female	47	27	Dead
45	CRC	III	Y	Medium		Male	70	21	Dead
46	CRC	II	Y	Medium	>3 cm	Female	67	36	Dead
47	CRC	III	Y	Medium	>3 cm	Male	73	21	Dead
48	CRC	III	Y	Low		Male	40	39	Dead
49	CRC	III	Y	Medium		Female	55	54	Dead
50	CRC	III	N	Medium	>3 cm	Female	53	51	Live
51	CRC	II	N	Low	>3 cm	Male	45	30	Dead
52	CRC	II	N	Medium	>3 cm	Male	65	33	Dead
53	CRC	II	N	Medium	>3 cm	Male	39	18	Dead
54	CRC	II	N	High	>3 cm	Male	47	27	Dead
55	CRC	II	Y	Medium	>3 cm	Female	72	60	Live
56	CRC	II	N	High	>3 cm	Male	60	27	Live
57	CRC	III	N	High		Male	49	36	Dead
58	CRC	II	N	High		Male	54	33	Dead
59	CRC	II	N	High		Male	41	60	Live
60	CRC	II	N	High	>3 cm	Male	70	51	Dead
61	CRC	II	Y	High	>3 cm	Female	45	48	Dead
62	CRC	II	N	Low		Male	44	45	Dead
63	CRC	II	N	Low		Male	56	45	Dead
64	CRC	II	N	Low		Male	68	33	Dead
65	CRC	II	Y	Low	>3 cm	Female	62	39	Dead
66	CRC	IV	N	High		Female	47	27	Dead
67	CRC	IV	N	High		Female	43	60	Live
68	CRC	II	N	High	>3 cm	Male	54	60	Live
69	CRC	III	N	Medium	>3 cm	Male	62	60	Live
70	CRC	II	N	Medium		Male	65	33	Dead
71	CRC	II	Y	High	>3 cm	Male	43	45	Dead
72	CRC	II	Y	High		Male	50	48	Dead
73	CRC	I	N	High	>3 cm	Male	65	51	Live
74	CRC	I	N	Low		Male	67	54	Dead
75	CRC	I	Y	High		Male	45	57	Dead
76	CRC	IV	N	High	>3 cm	Female	60	51	Dead
77	CRC	IV	N	High	>3 cm	Male	51	60	Live
78	CRC	I	N	Low	>3 cm	Male	53	48	Dead
79	CRC	I	N	High		Male	58	60	Live
80	CRC	I	Y	High	>3 cm	Male	50	39	Dead
81	CRC	III	N	High	>3 cm	Female	68	27	Live
82	CRC	I	Y	Low	>3 cm	Female	53	36	Dead
83	CRC	I	N	High		Male	46	30	Live
84	CRC	III	N	Low		Male	68	42	Dead
85	CRC	I	N	Low		Male	41	30	Dead
86	CRC	III	N	High		Male	45	57	Dead
87	CRC	III	N	Medium	>3 cm	Female	64	42	Dead
88	CRC	IV	N	Medium		Male	73	42	Live
89	CRC	I	N	High	>3 cm	Male	43	39	Dead
90	CRC	IV	Y	High		Female	58	45	Dead
91	CRC	I	N	Low	>3 cm	Female	62	42	Dead
92	CRC	III	N	High	>3 cm	Male	47	33	Live
93	CRC	I	Y	High	>3 cm	Male	65	36	Dead
94	CRC	I	N	High	>3 cm	Female	68	30	Dead
M – stands for metastasis; D – stands for differentiation; TS – stands for tumor size; CRC – colorectal cancer.

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Extracellular Vesicle-Transported Long Non-Coding RNA (LncRNA) X Inactive-Specific Transcript (XIST) in Serum is a Potential Novel Biomarker for Colorectal Cancer Diagnosis

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