Clinicopathological Characteristics and Prognosis of Nasopharyngeal Lymphoepithelial Carcinoma: A Population-Based Retrospective Study

31 August 2020: Database Analysis

Liu Xizhi ^1ABCDEF , Zhang Lifen ^1BCD , Duan Xueqin ^1CD , Zhang Wenwen ^1CD , Huang Shangke ^2EF , Luo Minna ^3EF , Zhao Xinhan ^1AG*

DOI: 10.12659/MSM.924492

Med Sci Monit 2020; 26:e924492

Table 1 Clinical characteristics of patients with nasopharyngeal lymphoepithelial carcinoma.

Characters	Primary cohort (n=392)		Validation cohort (n=146)
Characters	No. of patients	%	No. of patients	%
Gender
Male	281	72	35	24
Female	111	28	111	76
Age (years)
Children (	25	6	10	7
AYAs (18–34)	54	14	21	14
Adults (35–64)	251	64	95	65
Elderly (≥65)	62	16	20	14
Race
White	159	40	47	32
Black	57	15	11	8
Other/unknow	176	45	88	60
7 AJCC stage
I	66	17	39	27
II	110	28	41	28
III	114	29	55	37
IVA	32	8	7	5
IVB	47	12	4	3
IVC	23	6	0	0
Grade
II	2	1	0	0
III	57	14	36	25
IV	252	64	70	48
Unknow	81	21	40	27
Radiation sequence with surgery
No radiation or surgery	260	66	119	82
Radiation after surgery	129	33	25	17
Radiation prior to surgery	3	1	2	1
Surgery
Yes	72	18	30	21
No	320	82	116	79
Radiation
Yes	362	92	139	95
No	30	8	7	5
Chemotherapy
Yes	337	86	71	49
No	55	14	75	51
AYAs – adolescents and young adults; AJCC – American Joint Committee on Cancer.