31 August 2020 : Database Analysis
Clinicopathological Characteristics and Prognosis of Nasopharyngeal Lymphoepithelial Carcinoma: A Population-Based Retrospective Study
Liu Xizhi1ABCDEF, Zhang Lifen1BCD, Duan Xueqin1CD, Zhang Wenwen1CD, Huang Shangke2EF, Luo Minna3EF, Zhao Xinhan1AG*DOI: 10.12659/MSM.924492
Med Sci Monit 2020; 26:e924492
Table 1 Clinical characteristics of patients with nasopharyngeal lymphoepithelial carcinoma.
| Characters | Primary cohort (n=392) | Validation cohort (n=146) | ||
|---|---|---|---|---|
| No. of patients | % | No. of patients | % | |
| Gender | ||||
| Male | 281 | 72 | 35 | 24 |
| Female | 111 | 28 | 111 | 76 |
| Age (years) | ||||
| Children (<18) | 25 | 6 | 10 | 7 |
| AYAs (18–34) | 54 | 14 | 21 | 14 |
| Adults (35–64) | 251 | 64 | 95 | 65 |
| Elderly (≥65) | 62 | 16 | 20 | 14 |
| Race | ||||
| White | 159 | 40 | 47 | 32 |
| Black | 57 | 15 | 11 | 8 |
| Other/unknow | 176 | 45 | 88 | 60 |
| 7 AJCC stage | ||||
| I | 66 | 17 | 39 | 27 |
| II | 110 | 28 | 41 | 28 |
| III | 114 | 29 | 55 | 37 |
| IVA | 32 | 8 | 7 | 5 |
| IVB | 47 | 12 | 4 | 3 |
| IVC | 23 | 6 | 0 | 0 |
| Grade | ||||
| II | 2 | 1 | 0 | 0 |
| III | 57 | 14 | 36 | 25 |
| IV | 252 | 64 | 70 | 48 |
| Unknow | 81 | 21 | 40 | 27 |
| Radiation sequence with surgery | ||||
| No radiation or surgery | 260 | 66 | 119 | 82 |
| Radiation after surgery | 129 | 33 | 25 | 17 |
| Radiation prior to surgery | 3 | 1 | 2 | 1 |
| Surgery | ||||
| Yes | 72 | 18 | 30 | 21 |
| No | 320 | 82 | 116 | 79 |
| Radiation | ||||
| Yes | 362 | 92 | 139 | 95 |
| No | 30 | 8 | 7 | 5 |
| Chemotherapy | ||||
| Yes | 337 | 86 | 71 | 49 |
| No | 55 | 14 | 75 | 51 |
| AYAs – adolescents and young adults; AJCC – American Joint Committee on Cancer. | ||||






