20 July 2020 : Clinical Research
Predictive Value of Fibrinogen-to-Albumin Ratio for Post-Contrast Acute Kidney Injury in Patients Undergoing Elective Percutaneous Coronary Intervention
Can Wang1BCDE, Gaoye Li1F, Xiaomei Liang1C, Chunyu Qin1C, Qiuhu Luo1B, Rui Song1C, Wuxian Chen1AG*DOI: 10.12659/MSM.924498
Med Sci Monit 2020; 26:e924498
Table 1 Patients characteristics.
| PC-AKI (+) (n=43) | PC-AKI (−) (n=248) | P-value | |
|---|---|---|---|
| Age | 67±9 | 62±10 | 0.002 |
| BMI | 25.4±3.7 | 24.6±3.5 | 0.136 |
| Male gender | 31 (72%) | 202 (81%) | 0.156 |
| Smoking | 16 (37%) | 114 (46%) | 0.286 |
| Hypertension | 41 (95%) | 190 (77%) | 0.005 |
| Diabetes | 27 (63%) | 81 (33%) | <0.001 |
| Chronic heart failure | 26 (60%) | 77 (31%) | <0.001 |
| Hemoglobin (g/L) | 119±18 | 132±17 | <0.001 |
| NLR | 2.8 (1.9–3.8) | 2.2 (1.7–2.8) | 0.003 |
| Albumin (g/L) | 39.9±4.5 | 41.7±4.3 | 0.012 |
| Fibrinogen (g/L) | 4.2 (3.2–5.1) | 3.4 (2.9–4.1) | 0.001 |
| FAR | 10.2 (8.0–13.3) | 8.1 (7.0–9.8) | <0.001 |
| HbA1c (%) | 6.5 (5.8–7.4) | 6.3 (5.9–6.5) | 0.062 |
| Total cholesterol (mmol/L) | 4.64±1.06 | 4.45±1.06 | 0.268 |
| Triglycerides (mmol/L) | 1.70 (1.03–2.47) | 1.32 (0.97–2.16) | 0.103 |
| LDL-C (mmol/L) | 2.61±0.94 | 2.50±0.92 | 0.478 |
| Creatinine (umol/L) | 107 (84–119) | 88 (73–109) | 0.001 |
| eGFR (ml/min/1.73 m) | 60±20 | 76±20 | <0.001 |
| CK-MB (U/L) | 14 (10–19) | 13 (10–17) | 0.380 |
| LVEF (%) | 59 (41–69) | 66 (60–71) | <0.001 |
| Contrast volume | 150 (130–200) | 150 (130–200) | 0.976 |
| Data are expressed as mean±SD, or median (25–75 percentiles), or number (percentage). BMI – body mass index; CK-MB – creatine kinase MB form; eGFR – estimated glomerular filtration rate; FAR – fibrinogen to albumin ratio; HbA1c – hemoglobin A1c; LDL-C – low-density lipoprotein cholesterol; LVEF – left ventricular ejection fraction; NLR – neutrophil to lymphocyte ratio; PC-AKI – post-contrast acute kidney injury. | |||