15 August 2020 : Clinical Research
Analysis of Clinical Characteristics, Pathological Changes and Changes of Interleukin-6 (IL-6) and C-Reactive Protein (CRP) in Children with Castleman’s Disease
Chao Hu1AE, Yan Zou1BF*, Jing Pan1BD, Jiliang Yang1DF, Tianyou Yang1AG, Tianbao Tan1CE, Jiahao Li1CGDOI: 10.12659/MSM.924783
Med Sci Monit 2020; 26:e924783
Table 1 Comparison of serum IL-6 and CRP expressions between the 2 groups (χ̄±s).
| Group | IL-6 (ng/L) | CRP (mg/L) |
|---|---|---|
| Control group (n=20) | 5.1±1.4 | 2.0±0.5 |
| Observation group (n=15) | 41.6±9.2 | 6.7±2.8 |
| 35.179 | 16.402 | |
| 0.000 | 0.000 | |
| UCD (n=8) | 40.0±9.3 | 6.1±2.5 |
| MCD (n=7) | 43.4±7.2 | 6.5±2.3 |
| 0.7607 | 1.123 | |
| 0.4604 | 0.2819 | |
| Hyaline-vascular type (n=8) | 43.5±8.3 | 6.2±2.5 |
| Plasma-cell type (n=4) | 93.5±9.6 | 7.9±2.8 |
| Unclear pathological type (n=3) | 93.5±8.6 | 6.5±2.1 |
| 0.3953 | 0.6212 | |
| 0.6819 | 0.5537 | |
| IL-6 – interleukin-6; CRP – C-reactive protein; unicentric UCD – unicentric Castleman’s disease; MCD – multicentric Castleman’s disease. | ||