13 November 2020 : Database Analysis
Association of Thiamine Intake with Human Papillomavirus (HPV) Infection in American Women: A Secondary Data Analysis Based on the National Health and Nutrition Examination Survey from 2003 to 2016
Yue-xi Zhou1BCE, Fang-fang Zhu1BE, Chi Chen2C, Ying-xuan Zhang1D, Xiao-li Lv1F, Jing-wei Li1F, Song-ping Luo3AG*, Jie Gao3AGDOI: 10.12659/MSM.924932
Med Sci Monit 2020; 26:e924932
Table 2 The linear and nonlinear relationship between thiamine intake and HPV infection assessed by weighted univariate and multivariate logistic regression models.
| Exposure | Model 1β (95% CI) | Model 2β (95% CI) | Model 3β (95% CI) | GAM modelβ (95% CI) |
|---|---|---|---|---|
| HN HP | n=13471 | n=12089 | n=4170 | n=4170 |
| thiamine intake (mg) (log2 transform) | 0.83 (0.79, 0.86) | 0.87 (0.83, 0.91) | 0.87 (0.80, 0.95) | 0.87 (0.80, 0.95) |
| Thiamine intake (mg) (log2 transform) (quartile) | ||||
| Q1 | Ref | Ref | Ref | Ref |
| Q2 | 0.77 (0.70, 0.84) | 0.83 (0.75, 0.91) | 0.83 (0.69, 0.99) | 0.83 (0.70, 0.99) |
| Q3 | 0.68 (0.62, 0.75) | 0.76 (0.68, 0.84) | 0.73 (0.61, 0.87) | 0.74 (0.62, 0.88) |
| Q4 | 0.70 (0.63, 0.77) | 0.77 (0.69, 0.86) | 0.75 (0.62, 0.92) | 0.75 (0.62, 0.92) |
| P for trend | <0.0001 | <0.0001 | 0.0007 | 0.0009 |
| Model 1 – no covariates were adjusted; Model 2 – only sociodemographic variables were adjusted (body mass index, age, education, marital status, and ethnicity); Model 3 – all covariates presented in were adjusted; GAM Model – all continuous variables in the covariates were adjusted as smooth. | ||||