01 October 2020>: Database Analysis
Comparison of Bispectral Index-Guided Individualized Anesthesia with Standard General Anesthesia on Inadequate Emergence and Postoperative Delirium in Elderly Patients Undergoing Esophagectomy: A Retrospective Study at a Single Center
Yichen Yang 1ACDEF* , Chengjun Song 2BCDEF* , Chengwei Song 2ACDEF , Chengwen Li 3ACDEFG*DOI: 10.12659/MSM.925314
Med Sci Monit 2020; 26:e925314
Table 2 Comparison of bispectral values and anesthetic requirements between groups before and after propensity score matching.
Variable | Before matching | After matching | ||||
---|---|---|---|---|---|---|
Group I (n=66) | Group S (n=95) | P-value | Group I (n=58) | Group S (n=58) | P-value | |
BIS at baseline | 97 (94–97) | 97 (94–98) | 0.489 | 97 (94–97) | 97 (94–98) | 0.800 |
BIS at LOC | 75.0±5.5 | n.a. | n.a. | 74.8±5.6 | n.a. | n.a. |
BIS minimal during surgery | 47.6±6.5 | 38.0±7.3 | 0.000 | 48.1±6.6 | 38.1±7.8 | 0.000 |
BIS maximal during surgery | 68.2±6.2 | 60.0±6.3 | 0.000 | 68.4±6.4 | 60.3±5.0 | 0.000 |
BIS average during surgery | 57.9±5.4 | 49.3±5.4 | 0.000 | 58.3±5.6 | 49.2±5.4 | 0.000 |
Requirements of anesthetics during surgery | ||||||
Propofol for induction, mg | 75 (57.5–100) | 100 (75–120) | 0.000 | 75 (60–100) | 100 (75–120) | 0.003 |
Propofol for maintenance, mg·kg·h | 3.6±1.4 | 4.5±1.9 | 0.001 | 3.7±1.4 | 4.4±1.9 | 0.013 |
Sufentanil, μg/kg | 0.62±0.14 | 0.67±0.16 | 0.159 | 0.62±0.14 | 0.66±0.16 | 0.160 |
Remifentanil, μg·kg·h | 4.20 (4.11–4.28) | 4.15 (4.06–4.23) | 0.088 | 4.20 (4.11–4.27) | 4.15 (4.04–4.24) | 0.177 |
Cisatracurium, mg·kg·h | 0.126 (0.124–0.128) | 0.125 (0.123–0.128) | 0.413 | 0.126 (0.124–0.130) | 0.125 (0.123–0.127) | 0.235 |
Values are expressed as median (IQR) or mean±SD. Groups: I, BIS indices maintained at about 10 less than the BIS value at LOC; S, BIS indices maintained at 40–60. LOC – loss of consciousness; BIS – bispectral index; n.a. – not available. |