Vitamin D Attenuates Hypoxia-Induced Injury in Rat Primary Neuron Cells through Downregulation of the Dual Oxidase 1 (DUOX1) Gene

26 July 2020 : Laboratory Research

Panpan Cui^12BD, Yan Wang^1AC, Yanzhong Li^1AE*, Lei Ge^3F

DOI: 10.12659/MSM.925350

Med Sci Monit 2020; 26:e925350

Table 1 The sequences of DUOX1 siRNA (siDUOX1).

Name	Sequence
siDUOX1-1: 118–136	Sense: 5′-GCGAUUUGAUGGAUGGUAUTT-3′
siDUOX1-1: 118–136	Antisense: 5′-AUACCAUCCAUCAAAUCGCTT-3′

siDUOX1-2: 3124–3142	Sense: 5′-GCAGUUCAAGCGCUUCAUUTT-3′
siDUOX1-2: 3124–3142	Antisense: 5′-AAUGAAGCGCUUGAACUGCTT-3′

siDUOX1-3: 4254–4272	Sense: 5′-GCUGCCAAGUGUUCUGUAATT-3′
siDUOX1-3: 4254–4272	Antisense: 5′-UUACAGAACACUUGGCAGCTT-3′

siNC	Sense: 5′-CAGUACUUUUGUGUAGUACAA-3′
siNC	Antisense: 5′-UUGUACUACACAAAAGUACUG-3′