The Relationship Between Chronic Obstructive Pulmonary Disease and Cerebral Small Vessel Disease Assessed by Magnetic Resonance Imaging: A Case-Control Study from a Single Center in Beijing, China

Wei Qin; Jiangmei Yin; Lei Yang; Shuna Yang; Yue Li; Xuanting Li; Wenli Hu

doi:10.12659/MSM.925703

20 November 2020 : Clinical Research

The Relationship Between Chronic Obstructive Pulmonary Disease and Cerebral Small Vessel Disease Assessed by Magnetic Resonance Imaging: A Case-Control Study from a Single Center in Beijing, China

Wei Qin^1ABCDE, Jiangmei Yin^2BCDF, Lei Yang^1BCF, Shuna Yang^1BF, Yue Li^1CE, Xuanting Li^1EG, Wenli Hu^1E*

DOI: 10.12659/MSM.925703

Med Sci Monit 2020; 26:e925703

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Table 3 The results of multivariate logistic regression analysis between group membership (chronic obstructive pulmonary disease [COPD] group and control group) and cerebral small vessel disease (CSVD) markers.

	OR (95% CI)	P
WMH	2.467 (1.550–3.927)	<0.001
BG-EPVS	0.391 (0.246–0.621)	<0.001
CSO-EPVS	0.053 (0.021–0.138)	<0.001
Brain atrophy	0.978 (0.622–1.536)	0.922
WMH – white matter hyperintensities; BG-EPVS – basal ganglia enlarged perivascular spaces; CSO-EPVS – centrum semiovale enlarged perivascular spaces.

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The Relationship Between Chronic Obstructive Pulmonary Disease and Cerebral Small Vessel Disease Assessed by Magnetic Resonance Imaging: A Case-Control Study from a Single Center in Beijing, China

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