Retrospective Comparison of the Safety and Effectiveness of Dexmedetomidine Versus Standard of Care Before and During Cesarean Delivery in a Maternity Unit in Zhengzhou, China

24 October 2020 : Clinical Research

Wei Zhao^1ABF, Ling Ma^1ABDF, Jingjing Wang^2EFG*, Xiaoyan Shi^3ABCF

DOI: 10.12659/MSM.925709

Med Sci Monit 2020; 26:e925709

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Table 2 Measurement of pain during uterine contractions.

	Treatment cohorts
	DX: Dexmedetomidine before and during delivery + normal saline after delivery	SC: Normal saline before and during delivery + dexmedetomidine after delivery	CN: Normal saline before, during, and after delivery
No. women included	115	109	168
Time				q values
Time				P values	DX vs. SC	DX vs. CN	SC vs. SN
Immediately after delivery	1.75±0.22	1.77±0.24	1.81±0.26	0.108	N/A	N/A	N/A
6 h after delivery	3.47±0.24	3.55±0.26	3.51±0.28	0.077	N/A	N/A	N/A
12 h after delivery	3.42±0.29	3.48±0.29	3.52±0.41	0.060	N/A	N/A	N/A
1 day after delivery	2.23±0.15^*	2.31±0.17	2.38±0.21	<0.0001	6.931	9.569	1.883
Data are shown as mean±SD. One-way analysis of variance was performed followed by Tukey’s post hoc test for statistical analysis. P3.326 were considered significant. ^* Significantly less than in the CN cohort.

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