24 October 2020 : Clinical Research
Retrospective Comparison of the Safety and Effectiveness of Dexmedetomidine Versus Standard of Care Before and During Cesarean Delivery in a Maternity Unit in Zhengzhou, China
Wei Zhao1ABF, Ling Ma1ABDF, Jingjing Wang2EFG*, Xiaoyan Shi3ABCFDOI: 10.12659/MSM.925709
Med Sci Monit 2020; 26:e925709
Table 3 Measurement of pain during movement.
| Treatment cohorts | |||||||
|---|---|---|---|---|---|---|---|
| DX: Dexmedetomidine before and during delivery + normal saline after delivery | SC: Normal saline before and during delivery + dexmedetomidine after delivery | CN: Normal saline before, during, and after delivery | |||||
| No. women included | 115 | 109 | 168 | ||||
| Time | q values | ||||||
| P values | DX vs. SC | DX vs. CN | SC vs. SN | ||||
| Immediately after delivery | 2.01±0.18 | 2.04±0.17 | 2.08±0.31 | 0.054 | N/A | N/A | N/A |
| 6 h after delivery | 4.15±0.18 | 4.19±0.17 | 4.21±0.32 | 0.135 | N/A | N/A | N/A |
| 12 h after delivery | 3.52±0.24 | 3.59±0.25 | 3.60±0.33 | 0.054 | N/A | N/A | N/A |
| 1 day after delivery | 3.41±0.25* | 3.53±0.26 | 3.59±0.24 | <0.0001 | 5.106 | 8.460 | 2.775 |
| Data are shown as mean±SD. One-way analysis of variance was performed followed by Tukey’s post hoc test for statistical analysis. P3.326 were considered significant. N/A – not applicable. * Significantly less than in the CN cohort. | |||||||