30 September 2020 : Animal Research
Efficacy, Drug Sensitivity, and Safety of a Chronic Ocular Hypertension Rat Model Established Using a Single Intracameral Injection of Hydrogel into the Anterior Chamber
Huan Yu1BCE, Huimin Zhong2CDF, Junjue Chen1DF, Jun Sun1BF, Ping Huang3EF, Xing Xu3CE, Shouyue Huang1ADE, Yisheng Zhong1AG*DOI: 10.12659/MSM.925852
Med Sci Monit 2020; 26:e925852
Table 2 Summary of Flash Visual evoked potentials (F-VEP) test.
| Groups | N | Latency (ms) | Amplitude (μV) | P1 | P2 |
|---|---|---|---|---|---|
| Control | 6 | 62.23±1.65 | 7.14±0.73 | ||
| COH 2 weeks | 6 | 67.06±3.39 | 3.64±0.85 | 0.16 | 0.005 |
| COH 4 weeks | 6 | 73.02±4.31 | 3.25±0.49 | 0.017 | <0.001 |
| COH 8 weeks | 6 | 85.77±3.16 | 1.67±0.50 | <0.001 | <0.001 |
| P1=P value for the Chronic ocular hypertension (COH) 2/4/8 weeks – Control comparison group in latency; P2=P value for the COH 2/4/8 weeks – Control comparison group in amplitude. | |||||