25 September 2020 : Clinical Research
Clinical Characteristics and Risk Factors of Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Patients in Beijing, China: A Retrospective Study
Aibin Wang1ABCDE, Guiju Gao1ABE, Sa Wang1ABDEF, Meiling Chen2C, Fang Qian1B, Weiming Tang3BD, Yanli Xu1B, Rui Song1B, Liwei Zhuang4B, Xiaoyang Ma5B, Tianwei Zhao1B, Xiaodi Guo4B, Wei Li4B, Xudong Wang6B, Baoliang Li6B, Chun Hu6B, Zhihai Chen1ADE, Fujie Zhang1ADE*DOI: 10.12659/MSM.925974
Med Sci Monit 2020; 26:e925974
Table 4 The risk factors of ARDS.
| Clinical characteristics | Univariable OR (95% CI) | p value | Multivariable OR (95% CI) | p Value |
|---|---|---|---|---|
| Age, years | ||||
| >65 years (. 18–65 years) | 8.46 (3.14–22.77) | 0.000 | 4.75 (1.26–17.89) | 0.021 |
| Hypertension (. no hypertension) | 3.71 (2.72–220.82) | 0.010 | – | – |
| Maximum body temperature, °C | 6.83 (2.77–16.82) | 0.000 | 5.35 (1.38–20.76) | 0.015 |
| Day of body temperature recovery, Days | 1.15 (1.05–1.25) | 0.002 | – | – |
| Lopinavir/ritonavir therapy (NO – lopinavir/ritonavir) | 0.25 (0.10–0.62) | 0.003 | – | – |
| Lym count, 10/L | ||||
| >1.0 | 1 (ref) | – | – | |
| 0.5–1.0 | 2.71 (1.12–6.56) | 0.024 | 8.80 (2.22–34.99) | 0.002 |
| <0.5 | 31.88 (6.39–159.00) | 0.000 | 36.23 (4.63–283.48) | 0.001 |
| WBC – white blood cell; Neu – neutrophil; Lym – lymphocyte; HGB – hemoglobin; PLT – platelet; Bun – blood urea nitrogen; Cr – serum creatinine; ALT – alanine transaminase; AST – glutamate transaminase; LDH – lactate dehydrogenase; HBDH – hydroxybutyrate dehydrogenase; CK – creatine kinase; CKMB – myocardial creatine kinase isoenzyme; PT – prothrombin time; APTT – activated partial thromboplastin time; FIB – fibrinogen; TT – thrombin time; CRP – C-reactive protein; LAC – lactic acid; SAA – serum amylase-like protein; ESR – erythrocyte sedimentation rate. | ||||