25 September 2020: Clinical Research
Clinical Characteristics and Risk Factors of Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Patients in Beijing, China: A Retrospective Study
Aibin Wang 1ABCDE* , Guiju Gao 1ABE* , Sa Wang 1ABDEF* , Meiling Chen 2C* , Fang Qian 1B , Weiming Tang 3BD , Yanli Xu 1B , Rui Song 1B , Liwei Zhuang 4B , Xiaoyang Ma 5B , Tianwei Zhao 1B , Xiaodi Guo 4B , Wei Li 4B , Xudong Wang 6B , Baoliang Li 6B , Chun Hu 6B , Zhihai Chen 1ADE* , Fujie Zhang 1ADE*DOI: 10.12659/MSM.925974
Med Sci Monit 2020; 26:e925974
Table 4 The risk factors of ARDS.
| Clinical characteristics | Univariable OR (95% CI) | p value | Multivariable OR (95% CI) | p Value |
|---|---|---|---|---|
| Age, years | ||||
| >65 years (. 18–65 years) | 8.46 (3.14–22.77) | 0.000 | 4.75 (1.26–17.89) | 0.021 |
| Hypertension (. no hypertension) | 3.71 (2.72–220.82) | 0.010 | – | – |
| Maximum body temperature, °C | 6.83 (2.77–16.82) | 0.000 | 5.35 (1.38–20.76) | 0.015 |
| Day of body temperature recovery, Days | 1.15 (1.05–1.25) | 0.002 | – | – |
| Lopinavir/ritonavir therapy (NO – lopinavir/ritonavir) | 0.25 (0.10–0.62) | 0.003 | – | – |
| Lym count, 10/L | ||||
| >1.0 | 1 (ref) | – | – | |
| 0.5–1.0 | 2.71 (1.12–6.56) | 0.024 | 8.80 (2.22–34.99) | 0.002 |
| 31.88 (6.39–159.00) | 0.000 | 36.23 (4.63–283.48) | 0.001 | |
| WBC – white blood cell; Neu – neutrophil; Lym – lymphocyte; HGB – hemoglobin; PLT – platelet; Bun – blood urea nitrogen; Cr – serum creatinine; ALT – alanine transaminase; AST – glutamate transaminase; LDH – lactate dehydrogenase; HBDH – hydroxybutyrate dehydrogenase; CK – creatine kinase; CKMB – myocardial creatine kinase isoenzyme; PT – prothrombin time; APTT – activated partial thromboplastin time; FIB – fibrinogen; TT – thrombin time; CRP – C-reactive protein; LAC – lactic acid; SAA – serum amylase-like protein; ESR – erythrocyte sedimentation rate. | ||||