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25 September 2020: Clinical Research

Clinical Characteristics and Risk Factors of Acute Respiratory Distress Syndrome (ARDS) in COVID-19 Patients in Beijing, China: A Retrospective Study

Aibin Wang 1ABCDE* , Guiju Gao 1ABE* , Sa Wang 1ABDEF* , Meiling Chen 2C* , Fang Qian 1B , Weiming Tang 3BD , Yanli Xu 1B , Rui Song 1B , Liwei Zhuang 4B , Xiaoyang Ma 5B , Tianwei Zhao 1B , Xiaodi Guo 4B , Wei Li 4B , Xudong Wang 6B , Baoliang Li 6B , Chun Hu 6B , Zhihai Chen 1ADE* , Fujie Zhang 1ADE*

DOI: 10.12659/MSM.925974

Med Sci Monit 2020; 26:e925974

Table 4 The risk factors of ARDS.

Clinical characteristicsUnivariable OR (95% CI)p valueMultivariable OR (95% CI)p Value
Age, years
>65 years (. 18–65 years)8.46 (3.14–22.77)0.0004.75 (1.26–17.89)0.021
Hypertension (. no hypertension)3.71 (2.72–220.82)0.010
Maximum body temperature, °C6.83 (2.77–16.82)0.0005.35 (1.38–20.76)0.015
Day of body temperature recovery, Days1.15 (1.05–1.25)0.002
Lopinavir/ritonavir therapy (NO – lopinavir/ritonavir)0.25 (0.10–0.62)0.003
Lym count, 10/L
 >1.01 (ref)
 0.5–1.02.71 (1.12–6.56)0.0248.80 (2.22–34.99)0.002
31.88 (6.39–159.00)0.00036.23 (4.63–283.48)0.001
WBC – white blood cell; Neu – neutrophil; Lym – lymphocyte; HGB – hemoglobin; PLT – platelet; Bun – blood urea nitrogen; Cr – serum creatinine; ALT – alanine transaminase; AST – glutamate transaminase; LDH – lactate dehydrogenase; HBDH – hydroxybutyrate dehydrogenase; CK – creatine kinase; CKMB – myocardial creatine kinase isoenzyme; PT – prothrombin time; APTT – activated partial thromboplastin time; FIB – fibrinogen; TT – thrombin time; CRP – C-reactive protein; LAC – lactic acid; SAA – serum amylase-like protein; ESR – erythrocyte sedimentation rate.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750