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08 September 2020: Clinical Research

Serum-Soluble ST2 Is a Novel Biomarker for Evaluating Left Atrial Low-Voltage Zone in Paroxysmal Atrial Fibrillation

Zefeng Wang 1ACDE , Liting Cheng 1BCD , Junmeng Zhang 1AD , Zhuo Liang 1CD , Ruiqing Dong 2B , Fei Hang 1B , Xinlu Wang 1B , Ziyu Wang 1B , Yongquan Wu 1AD* , Jie Du 3ADE*

DOI: 10.12659/MSM.926221

Med Sci Monit 2020; 26:e926221

Table 1 Comparison of baseline clinical materials.

Group A (n=125)Group B (n=52)P valve
Age, y56.4±9.462.4±9.30.002
Male, n (%)87 (69.6%)36 (69.2%)0.961
BMI, kg/m31.4±7.032.3±8.70.501
AF duration, y24 (12, 48)24 (12, 48)0.789
Hypertension, n (%)70 (56.0%)27 (51.9%)0.620
Diabetes, n (%)24 (19.2%)8 (6.4%)0.548
CHD, n (%)16 (12.8%)3 (5.8%)0.169
ALT, U/L23.9±10.225.9±10.20.646
AST, U/L24.1±8.722.7±5.80.284
eGFR92.0±18.498.2±19.10.046
CREA, mol/L72.0±16.869.1±14.80.272
UA, mol/L343.4±100.9340.7±92.00.865
GLU, mmol/L5.9±1.65.2±0.80.093
TCHO, mmol/L4.7±1.74.6±1.20.682
LDL, mmol/L2.9±1.02.9±1.00.888
HDL, mmol/L1.2±0.21.1±0.30.278
TG, mmol/L1.8±1.11.7±0.90.494
hs CRP, mg/L0.9 (0.6,2.1)1.0 (0.6,2.0)0.964
LAAP-diameter, mm40.4±5.141.6±5.00.157
EF,%61.6±6.060.3±5.50.078
Normally distributed continuous variables are expressed as mean±standard deviation; non-uniformly distributed data are expressed as median (Q1, Q3); numbers are presented as number of patients (%). BMI – body mass index; AF – atrial fibrillation; CHD – coronary heart disease; ALT – alanine transaminase; AST – aspartate aminotransferase; eGFR – estimated glomerular filtration rate; CREA – creatinine; UA – uric acid; GLU – glucose; TCHO – total cholesterol; LDL – low-density lipoprotein; HDL – high-density lipoprotein; TG – triglyceride; LAAP-diameter – left atrial anteroposterior diameter; EF – ejection fraction.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750