16 September 2020 : Clinical Research
Efficacy and Safety of Neuromuscular Blockade in Overweight Patients Undergoing Nasopharyngeal Surgery
Lingxia Niu1BCE, Yu Wang1ADEF, Chunlin Yao1B, Yan Sun1BF, Shanglong Yao1A, Yun Lin1AG*DOI: 10.12659/MSM.926452
Med Sci Monit 2020; 26:e926452
Table 3 Changes in hemodynamic variables among the 3 groups.
| Change | Group RS (n=34) | Group RN (n=34) | Group CN (n=34) | P |
|---|---|---|---|---|
| C1 | 19 (12) | 14 (12) | 20 (12) | 0.09 |
| C2 | 20 (14) | 20 (13) | 18 (13) | 0.70 |
| C3 | 15 (12) | 16 (10) | 12 (9) | 0.21 |
| C4 | 8 (6),* | 19 (15) | 20 (15) | 0.00 |
| C1 | 13 (9) | 10 (7)*** | 16 (9) | 0.01 |
| C2 | 14 (11) | 14 (11) | 12 (9) | 0.61 |
| C3 | 13 (8) | 12 (7) | 10 (7) | 0.19 |
| C4 | 8 (5)** | 10 (10) | 13 (10) | 0.04 |
| C1 | 15 (9) | 11 (8) | 17 (10) | 0.02 |
| C2 | 16 (11) | 15 (12) | 14 (10) | 0.72 |
| C3 | 13 (8) | 12 (8) | 10 (7) | 0.16 |
| C4 | 6 (5),* | 13 (11) | 15 (11) | 0.00 |
| C1 | 10 (8) | 9 (7) | 9 (7) | 0.72 |
| C2 | 11 (7) | 10 (7) | 13 (10) | 0.37 |
| C3 | 5 (4) | 6 (6) | 7 (9) | 0.51 |
| C4 | 7 (7),* | 14 (11) | 19 (11) | 0.00 |
| Multiple comparisons using Tukey honest significant difference test. was used to indicate the difference between the 3 groups; * statistically significant difference between Group RS and Group RN (P-value ** statistically significant difference between Group RS and Group CN (P-value *** statistically significant difference between Group RN and Group CN (P-value The absolute values of hemodynamic changes of nNMBAs after 1 min, 5 min, and 10 min of administration were C1, C2, and C3, respectively. The absolute values of hemodynamic changes of muscle relaxant antagonist from administration to extubation were C4; SBP – systolic blood pressure; DBP – diastolic blood pressure; MAP – mean arterial pressure; HR – heart rate. | ||||