04 October 2020 : Clinical Research
The Potential Role of Lung-Protective Ventilation in Preventing Postoperative Delirium in Elderly Patients Undergoing Prone Spinal Surgery: A Preliminary Study
Jing Wang1ABCEF, Lian Zhu2ABCEF, Yanan Li1BCE, Chunping Yin1BCE, Zhiyong Hou2CEF, Qiujun Wang1ADEG*DOI: 10.12659/MSM.926526
Med Sci Monit 2020; 26:e926526
Table 1 Demographic and clinical characteristics of patients who received LPV or conventional MV and rates of cerebral desaturation and postoperative delirium (POD).
| Characteristics | MV Group (n=32) | LPV Group (n=32) | P-value |
|---|---|---|---|
| Age (years), mean±SD | 68.8±2.2 | 69.4±3.0 | 0.350 |
| Sex (Male/Female), n | 11/21 | 12/20 | 0.794 |
| ASA (I/II/III), n | 9/21/2 | 11/17/4 | 0.607 |
| Preoperative MMSE score, mean±SD | 26.8±1.9 | 26.5±1.5 | 0.519 |
| BMI (kg/m), mean±SD | 24.0±1.5 | 23.9±1.7 | 0.846 |
| PBW (kg), M (Q) | 57 (14) | 54 (16) | 0.710 |
| Hypertension, n (%) | 14 (44) | 15 (47) | 0.802 |
| Diabetes, n (%) | 7 (22) | 6 (19) | 0.756 |
| Coronary heart disease, n (%) | 4 (13) | 4 (13) | 1.000 |
| Blood loss (ml), mean±SD | 438±133 | 409±132 | 0.388 |
| Urine output (ml), mean±SD | 499±176 | 507±222 | 0.877 |
| Infusion volume (ml), mean±SD | 1902±263 | 1909±201 | 0.894 |
| Anesthesia duration (min), mean±SD | 153±27 | 159±26 | 0.392 |
| Operation duration (min), mean±SD | 114±27 | 117±25 | 0.690 |
| Prevalence of cerebral desaturation, n (%) | 10 (31) | 3 (9) | 0.030 |
| Prevalence of POD, n (%) | 8 (25) | 2 (6) | 0.039 |
| ASA – American Society of Anesthesiologists; MMSE – Mini-mental State Examination; BMI – body mass index; PBW – predicted body weight; POD – postoperative delirium; SD – standard deviation; M(Q) – median (interquartile range); n – number of patients; MV – conventional mechanical ventilation; LPV – lung-protective ventilation. | |||