Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

04 October 2020: Clinical Research

The Potential Role of Lung-Protective Ventilation in Preventing Postoperative Delirium in Elderly Patients Undergoing Prone Spinal Surgery: A Preliminary Study

Jing Wang 1ABCEF* , Lian Zhu 2ABCEF* , Yanan Li 1BCE , Chunping Yin 1BCE , Zhiyong Hou 2CEF , Qiujun Wang 1ADEG*

DOI: 10.12659/MSM.926526

Med Sci Monit 2020; 26:e926526

Table 1 Demographic and clinical characteristics of patients who received LPV or conventional MV and rates of cerebral desaturation and postoperative delirium (POD).

CharacteristicsMV Group (n=32)LPV Group (n=32)P-value
Age (years), mean±SD68.8±2.269.4±3.00.350
Sex (Male/Female), n11/2112/200.794
ASA (I/II/III), n9/21/211/17/40.607
Preoperative MMSE score, mean±SD26.8±1.926.5±1.50.519
BMI (kg/m), mean±SD24.0±1.523.9±1.70.846
PBW (kg), M (Q)57 (14)54 (16)0.710
Hypertension, n (%)14 (44)15 (47)0.802
Diabetes, n (%)7 (22)6 (19)0.756
Coronary heart disease, n (%)4 (13)4 (13)1.000
Blood loss (ml), mean±SD438±133409±1320.388
Urine output (ml), mean±SD499±176507±2220.877
Infusion volume (ml), mean±SD1902±2631909±2010.894
Anesthesia duration (min), mean±SD153±27159±260.392
Operation duration (min), mean±SD114±27117±250.690
Prevalence of cerebral desaturation, n (%)10 (31)3 (9)0.030
Prevalence of POD, n (%)8 (25)2 (6)0.039
ASA – American Society of Anesthesiologists; MMSE – Mini-mental State Examination; BMI – body mass index; PBW – predicted body weight; POD – postoperative delirium; SD – standard deviation; M(Q) – median (interquartile range); n – number of patients; MV – conventional mechanical ventilation; LPV – lung-protective ventilation.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750