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04 October 2020: Clinical Research

The Potential Role of Lung-Protective Ventilation in Preventing Postoperative Delirium in Elderly Patients Undergoing Prone Spinal Surgery: A Preliminary Study

Jing Wang 1ABCEF* , Lian Zhu 2ABCEF* , Yanan Li 1BCE , Chunping Yin 1BCE , Zhiyong Hou 2CEF , Qiujun Wang 1ADEG*

DOI: 10.12659/MSM.926526

Med Sci Monit 2020; 26:e926526

Table 2 Blood gas parameters over time in patients who received LPV or conventional MV (n=32 each).

GroupT0T1T2T3T4
pHMV7.43±0.047.41±0.057.41±0.047.38±0.057.33±0.06
LPV7.43±0.057.40±0.077.38±0.05* 7.37±0.057.33±0.08
PaO (mmHg)MV95 (16)344 (131)371 (128)372 (164)112 (48)
LPV92 (15)406 (103)* 417 (95)407 (118)162 (138)*
PaCO (mmHg)MV36±436±636±539±645±8
LPV36±438±740±6* 40±545±10
SaO (%)MV97.1 (1.7)99.6 (0.3)99.6 (0.5)99.6 (0.5)97.6 (2.5)
LPV97.0 (2.0)99.7 (0.4)* 99.7 (0.4)99.7 (0.3)98.8 (1.9)*
PaO/FiO (mmHg)MV95 (16)344 (131)371 (128)372 (164)112 (48)
LPV92 (15)406 (103)* 417 (95)407 (118)162 (138)*
Values expressed as mean±standard deviation or as median (interquartile range).
*
T – immediately before anesthesia induction; T – 10 min after turning over; T – 60 min after turning over; T – immediately after the operation; T – 15 min after extubation; MV – conventional mechanical ventilation; LPV – lung-protective ventilation.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750