The Potential Role of Lung-Protective Ventilation in Preventing Postoperative Delirium in Elderly Patients Undergoing Prone Spinal Surgery: A Preliminary Study

04 October 2020 : Clinical Research

Jing Wang^1ABCEF, Lian Zhu^2ABCEF, Yanan Li^1BCE, Chunping Yin^1BCE, Zhiyong Hou^2CEF, Qiujun Wang^1ADEG*

DOI: 10.12659/MSM.926526

Med Sci Monit 2020; 26:e926526

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Table 3 Preoperative and postoperative concentrations of GFAP, IL-6, and IL-10 in patients who received LPV or conventional MV (n=32 each).

	Group	Preoperative	Postoperative
GFAP (ng/ml)	MV	0.159±0.030	1.080±0.303
GFAP (ng/ml)	LPV	0.162±0.029	0.703±0.225^*
IL-6 (pg/mL)	MV	8.5±2.4	31.5±7.2
IL-6 (pg/mL)	LPV	8.5±2.1	23.1±4.7^*
IL-10 (pg/mL)	MV	18±9	58±16
IL-10 (pg/mL)	LPV	18±10	75±24^*
Values expressed as mean±standard deviation. ^* IL-6 – interleukin-6; IL-10 – interleukin-10; GFAP – glial fibrillary acidic protein; MV – conventional mechanical ventilation; LPV – lung-protective ventilation.

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