26 September 2020 : Database Analysis
Prognostic Value of Acute-On-Chronic Liver Failure (ACLF) Score in Critically Ill Patients with Cirrhosis and ACLF
Xinran Lin1ABCDEF, Xielin Huang2ABCDEF, Li Wang1BC, Shuyi Feng1B, Xiaofu Chen1BC, Weimin Cai1B, Zhiming Huang1A*DOI: 10.12659/MSM.926574
Med Sci Monit 2020; 26:e926574
Table 6 Multivariate Cox regression analysis of the effect of AARC ACLF on 90-day mortality.
| Variables | Unadjusted | Adjusted model I | Adjusted model II | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P | |
| AARC ACLF | 1.434 | 1.335, 1.539 | <0.001 | 1.433 | 1.332, 1.542 | <0.001 | 1.375 | 1.247, 1.516 | <0.001 |
| AARC ACLF grade | |||||||||
| 1 | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
| 2 | 2.922 | 2.012, 4.245 | <0.001 | 2.940 | 2.013, 4.293 | <0.001 | 1.949 | 1.201.3.163 | 0.002 |
| 3 | 6.295 | 4.119, 9.621 | <0.001 | 6.070 | 3.931, 9.373 | <0.001 | 4.432 | 2.591, 7.583 | <0.001 |
| Adjust I model was adjusted for: age, sex, and ethnicity; adjust II model was adjusted for: age, sex, ethnicity, MAP, PaO2/FiO2, 24 h urine output, blood urea nitrogen, albumin, sodium, potassium, ventilator, white blood cell, vasopressor used, renal replacement therapy, variceal bleeding, ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome. CI – confidence interval; HR – hazard ratio. | |||||||||