Prognostic Value of Acute-On-Chronic Liver Failure (ACLF) Score in Critically Ill Patients with Cirrhosis and ACLF

26 September 2020 : Database Analysis

Xinran Lin^1ABCDEF, Xielin Huang^2ABCDEF, Li Wang^1BC, Shuyi Feng^1B, Xiaofu Chen^1BC, Weimin Cai^1B, Zhiming Huang^1A*

DOI: 10.12659/MSM.926574

Med Sci Monit 2020; 26:e926574

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Supplementary Table 1 Diagnostic accuracy of scoring systems at cutoff points and at different time periods in ACLF patients.

Prognostic models	28-day AUROC	P value*	90-day AUROC	P value*	180-day AUROC	P value*
AARC ACLF	0.704	–	0.679	–	0.690	–
Child-Pugh score	0.549		0.526		0.524
MELD	0.666	0.297	0.660	0.589	0.690	0.535
MELD-Na	0.656	0.247	0.645	0.417	0.643	0.264
SOFA	0.688	0.703	0.679	0.998	0.668	0.984
CLIF-SOFA	0.651	0.089	0.640	0.180	0.649	0.167
CLIF-C ACLFs	0.719	0.670	0.694	0.665	0.699	0.792
AUROC – area under the receiver operating characteristic curve; MELD – model for end-stage liver disease; SOFA – Sequential Organ Failure Assessment; CLIF-SOFA – Chronic Liver Failure-Sequential Organ Failure Assessment Score. ^* DeLong test was used to compare the performance of each scoring systems with AARC ACLF.

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