03 November 2020 : Clinical Research
Chromogranin A: A Valuable Serum Diagnostic Marker for Non-Insulinoma Neuroendocrine Tumors of the Pancreas in a Chinese Population
Liwen Hong1AE, Yuan Wang2BD, Tianyu Zhang1CF, Chen Zhang1BC, Lei Wang1AD, Liying Wang3EG*, Zhengting Wang1AG, Jie Zhong1AGDOI: 10.12659/MSM.926635
Med Sci Monit 2020; 26:e926635
Table 3 Clinicopathological factors and serum CgA concentrations in patients with P-NETs.
| Factor | Total (n=73) | <Cut-off (n=28) | ≥Cut-off (n=45) | P-value | Logistic χ2 | P-value |
|---|---|---|---|---|---|---|
| Age (%) | ||||||
| ≥49(years) | 37 | 14 (37.8%) | 23 (62.2%) | 1 | ||
| <49(years) | 36 | 14 (38.9%) | 22 (61.1%) | |||
| Sex (%) | ||||||
| Male | 29 | 13 (44.8%) | 16 (55.2%) | 0.462 | ||
| Female | 44 | 15 (34.1%) | 29 (65.9%) | |||
| P-NETs subtype | <0.01 | 18.4 | <0.001* | |||
| Insulinoma | 43 | 24 (55.8%) | 19 (44.2%) | |||
| Non-insulinoma | 30 | 4 (13.3%) | 26 (86.7%) | |||
| Histological grade (%) | 0.143 | 0.015 | 0.902 | |||
| G1–G2 | 65 | 27 (41.5%) | 38 (58.5%) | |||
| G3 | 8 | 1 (12.5%) | 7 (87.5%) | |||
| Liver metastasis (%) | 0.023* | 14.6 | <0.001* | |||
| Yes | 12 | 1 (8.3%) | 11 (91.6%) | |||
| No | 61 | 27 (44.3%) | 34 (55.7%) | |||
| * | ||||||