03 November 2020>: Clinical Research
Chromogranin A: A Valuable Serum Diagnostic Marker for Non-Insulinoma Neuroendocrine Tumors of the Pancreas in a Chinese Population
Liwen Hong 1AE* , Yuan Wang 2BD* , Tianyu Zhang 1CF , Chen Zhang 1BC , Lei Wang 1AD , Liying Wang 3EG* , Zhengting Wang 1AG* , Jie Zhong 1AGDOI: 10.12659/MSM.926635
Med Sci Monit 2020; 26:e926635
Table 3 Clinicopathological factors and serum CgA concentrations in patients with P-NETs.
Factor | Total (n=73) | <Cut-off (n=28) | ≥Cut-off (n=45) | P-value | Logistic χ2 | P-value |
---|---|---|---|---|---|---|
Age (%) | ||||||
≥49(years) | 37 | 14 (37.8%) | 23 (62.2%) | 1 | ||
36 | 14 (38.9%) | 22 (61.1%) | ||||
Sex (%) | ||||||
Male | 29 | 13 (44.8%) | 16 (55.2%) | 0.462 | ||
Female | 44 | 15 (34.1%) | 29 (65.9%) | |||
P-NETs subtype | 18.4 | * | ||||
Insulinoma | 43 | 24 (55.8%) | 19 (44.2%) | |||
Non-insulinoma | 30 | 4 (13.3%) | 26 (86.7%) | |||
Histological grade (%) | 0.143 | 0.015 | 0.902 | |||
G1–G2 | 65 | 27 (41.5%) | 38 (58.5%) | |||
G3 | 8 | 1 (12.5%) | 7 (87.5%) | |||
Liver metastasis (%) | 0.023* | 14.6 | * | |||
Yes | 12 | 1 (8.3%) | 11 (91.6%) | |||
No | 61 | 27 (44.3%) | 34 (55.7%) | |||
* |