The Prognosis of Preterm Infants Born at the Threshold of Viability: Fog Over the Gray Zone – Population-Based Studies of Extremely Preterm Infants

10 December 2020 : Review article

Eszter Fanczal^1AE, Botond Berecz^1A, Annamária Szijártó^1A, Ákos Gasparics^1AD*, Péter Varga^1ABCEF

DOI: 10.12659/MSM.926947

Med Sci Monit 2020; 26:e926947

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Table 1 Selected large population-based studies on extremely preterm infants.

Study	Country/State	Years of the study	Gestational age	The number of all infants	The number of actively treated infants
EPIBEL []⁴	Belgium	1999–2000	22–26	525	303
NEPS1 []¹⁶	Norway	1999–2000	22–27	638	464
NEPS2 []¹⁷	Norway	2013–2014	22–26	275	251
Kugelman []⁷	Israel	1995–2008	23–26	4408	–
Agarwal []⁸	Singapore	2000–2009	23–28	–	887
EPICURE []¹⁸	UK	2006	22–26	3133	1686
EXPRESS []¹⁰	Sweden	2004–2007	22–26	–	707
Ishii []¹¹	Japan	2003–2005	22–25	–	1057
Doyle []¹²	Victoria State (Australia)	2005	22–27	–	270
Su []¹³	Taiwan	2007–2012	23–28	–	1718
EPIPAGE-2 []⁵	France	2011	22–26	–	1054
Stoll []¹⁴	USA	2008–2012	22–28	–	8877
Anderson []⁶	California	2007–2011	22–28	6009	5340
EPI-SEN []¹⁵	Spain	2007–2011	22–26	2937	2734
Fischer []⁹	Swiss	2000–2004	22–25	516	–
^* These studies were divided to several periods. Data were reviewed only from the last period (shown in the table) of these studies.

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