11 December 2020 : Review article
Preoperative Intranasal Decolonization with Topical Povidone-Iodine Antiseptic and the Incidence of Surgical Site Infection: A Review
Vidmi Taolam Martin1ABCDEF, Mohamed Abdullahi Abdi1ABEF, Jie Li1BCEF, Dongtai Li1BCDF, Zhaozhen Wang1BCDE, Xianliao Zhang1BDEF, Welera Haissou Elodie2BCEF, Bo Yu1ABCDEF*DOI: 10.12659/MSM.927052
Med Sci Monit 2020; 26:e927052
Table 1 Clinical characteristics of a decontamination protocol on surgical site infection in patients undergoing surgery from included studies.
| Fisrt author | Participants | Study design | Intervention | P value |
|---|---|---|---|---|
| Bebko SP [], 201521 | 365 | Prospective clinical study | Chlorhexidine washcloths 2% (one time the night before and the morning of the operation day)Oral rinse 0.12% (one time the night before and the morning of the operation day)Intranasal povidone-iodine solution 5% (one time the morning of the operation day) | .02 |
| Phillips M [], 201622 | 842 | Randomized open label trial | Intranasal povidone-iodine solution 5% (4 applications, within 2 hours of the surgical incision)Chlorhexidine wipes 2% (6 applications, one time the evening before and the morning of the operation day) | .1 |
| Rezapoor M [], 201723 | 143 | Randomized, placebo-controlled study | Intranasal povidone-iodine solution 5% (one time the morning of the operation day) | .003 |
| Urias DS [], 201824 | 962 | Retrospective review | Intranasal povidone-iodine solution 5% (2 applications in each nostril, one time the morning of the operation day)Bathing with 2% CHG washcloths or Dynahex 4% CHG solution (one time the night before operation, if possible, and the morning of the operation day) | .020 |
| Peng HM, [], 201825 | 545 | Prospective cross-sectional study | 5% povidone-iodine nasal (both nostrils twice a day for 5 days prior to the surgery)Chlorhexidine gluconate (baths for five days before the operation) | <.001 |
| CHG – chlorhexidine. | ||||