The Safety and Efficacy of Apatinib Treatment in Addition to Concurrent Chemoradiotherapy in Patients with Nonoperative Locally Advanced Esophageal Squamous Cell Carcinoma

27 November 2020 : Clinical Research

Lijun Hu^1ABCDEF*, Ze Kong^1BCDF, Qinghong Meng^1BCD, Jianlin Wang^1BCF, Mengyun Zhou^1BC, Jingping Yu^1ACEG, Xiaodong Jiang^2ACEG

DOI: 10.12659/MSM.927221

Med Sci Monit 2020; 26:e927221

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Table 3 Cox multivariate regression analysis of the prognostic factors for nonoperative esophageal squamous cell carcinoma patients.

	Overall survival		Progression-free survival
	HR (95% CI)	P	HR (95% CI)	P
T staging
T	1 (Reference)	0.006	1 (Reference)	0.045
T	2.108 (1.119, 3.973)	0.224	1.644 (1.001, 2.999)	0.035
T	3.275 (1.529, 7.013)	0.002	2.385 (1.147, 4.960)	0.020
Short-term efficacy
CR	1 (Reference)	0.000	1 (Reference)	0.000
PR	3.654 (1.256, 10.629)	0.017	3.539 (1.327, 9.439)	0.012
SD	51.519 (13.744, 193.116)	0.000	31.080 (9.147, 105.598)	0.000
CR – complete remission; HR – hazards ratio; PR – partial remission; SD – stable disease.

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