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20 July 2021: Clinical Research

Risk Prediction Model Based on Biomarkers of Remodeling in Patients with Acute Anterior ST-Segment Elevation Myocardial Infarction

Zeyan Liu 12ABCDEF , Lijun Liu 1E* , Jinglin Cheng 2BCF , Hao Zhang 2FG

DOI: 10.12659/MSM.927404

Med Sci Monit 2021; 27:e927404

Table 6 Diagnostic performance of the prediction model.

VariableAUC (95% CI)SDSensitivity (95% CI)Specificity (95% CI)ZP
Model 10.978 (0.955–0.991)0.00794.07 (88.7–97.4)92.42 (87.8–95.7)
Model 20.970 (0.946–0.986)0.00995.56 (90.6–98.4)89.90 (84.8–93.7)1.0920.275
No. stenosed coronary vessels0.650 (0.597–0.702)0.027100.00 (97.3–100.00)0.00 (0.0–1.8)12.151
LVEDV0.876 (0.836–0.910)0.01889.63 (83.2–94.2)69.19 (62.3–75.5)6.269
LVEF0.684 (0.631–0.734)0.01860.00 (51.2–68.3)73.23 (66.5–79.3)9.863
TGF-β at admission0.696 (0.644–0.745)0.02975.56 (67.4–82.5)57.58 (50.4–64.6)9.872
cTnI at admission0.913 (0.877–0.941)0.01988.15 (81.5–93.1)92.93 (88.4–96.1)3.0400.002
3-d cTnI0.945 (0.914–0.967)0.01290.37 (84.1–94.8)85.35 (79.6–90.0)7.962
3-d cTnI – cardiac troponin I 3 d after admission; AUC – area under the curve; CI – confidence interval; LVEDV – left ventricular end-diastolic volume; LVEF – left ventricular ejection fraction; SD – standard deviation; TGF-β – transforming growth factor-beta.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750