Efficacy of 5-Aminolevulinic Acid (ALA)-Photodynamic Therapy (PDT) in Refractory Vulvar Lichen Sclerosus: Preliminary Results

07 January 2021 : Clinical Research

Fenghua Zhang^1ABCEF, Daoyun Li^2BCD, Lijuan Shi^2BC, Yijia Gu^2C, Yun Xu^2AEG*, Changping Wu^345ACEG

DOI: 10.12659/MSM.927406

Med Sci Monit 2021; 27:e927406

Background Material and Methods Results Discussion Conclusions References

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Table 1 Demographics and baseline characteristics of patients.

Characteristic	Value
Age (years), mean±SD	48.2±11.5
Gender
Postmenopausal women	15 (50%)
Perimenopausal women	15 (50%)
Duration (months), mean±SD	81.3±68.1
Macroscopic characteristics of lesions atrophy	30
Hyperkeratosis	30 (100%)
Depigmentation	30 (100%)
Sclerosis	19 (63%)
Previous treatment	23 (77%)
Topical corticosteroids	22 (73%)
Topical calcineurin inhibitors	0 (0%)
Estrogens	0 (0%)
Local injection	0 (0%)
UVA1	0 (0%)
Others	1 (3%)

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