07 January 2021 : Clinical Research
Efficacy of 5-Aminolevulinic Acid (ALA)-Photodynamic Therapy (PDT) in Refractory Vulvar Lichen Sclerosus: Preliminary Results
Fenghua Zhang1ABCEF, Daoyun Li2BCD, Lijuan Shi2BC, Yijia Gu2C, Yun Xu2AEG*, Changping Wu345ACEGDOI: 10.12659/MSM.927406
Med Sci Monit 2021; 27:e927406
Table 2 The clinical manifestation, lesion size, and scores before treatment and at the 6-month follow-up.
| No | Baseline | Lesions size at baseline | Total scores | |||||
|---|---|---|---|---|---|---|---|---|
| Atrophy | Depigmentation | Hyperkertosis | Sclerosis | <30% | 30–60% | >60% | ||
| 1 | 2 | 3 | 1 | 1 | 0 | 0 | 1.5 | 12.5 |
| 2 | 1 | 2 | 2 | 1 | 0 | 1 | 0 | 7 |
| 3 | 2 | 2 | 1 | 2 | 0 | 0 | 1.5 | 8.5 |
| 4 | 3 | 3 | 3 | 2 | 0 | 0 | 1.5 | 12.5 |
| 5 | 2 | 2 | 2 | 2 | 0 | 0 | 1.5 | 9.5 |
| 6 | 3 | 3 | 3 | 3 | 0 | 0 | 1.5 | 13.5 |
| 7 | 1 | 2 | 2 | 1 | 0 | 0 | 1.5 | 7.5 |
| 8 | 2 | 3 | 3 | 1 | 0 | 0 | 1.5 | 10.5 |
| 9 | 2 | 2 | 2 | 1 | 0 | 0 | 1.5 | 8.5 |
| 10 | 2 | 2 | 3 | 1 | 0 | 0 | 1.5 | 9.5 |
| 11 | 2 | 2 | 2 | 1 | 0 | 0 | 1.5 | 8.5 |
| 12 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 5 |
| 13 | 2 | 2 | 2 | 2 | 0 | 1 | 0 | 9 |
| 14 | 2 | 3 | 2 | 2 | 0 | 0 | 1.5 | 10.5 |
| 15 | 3 | 3 | 3 | 3 | 0 | 0 | 1.5 | 13.5 |
| 16 | 2 | 2 | 3 | 2 | 0 | 0 | 1.5 | 10.5 |
| 17 | 2 | 2 | 2 | 2 | 0 | 0 | 1.5 | 9.5 |
| 18 | 1 | 3 | 1 | 0 | 0 | 1 | 0 | 6 |
| 19 | 2 | 2 | 2 | 3 | 0 | 1 | 0 | 10 |
| 20 | 2 | 2 | 2 | 2 | 0.5 | 0 | 0 | 8.5 |
| 21 | 2 | 3 | 2 | 2 | 0 | 0 | 1.5 | 10.5 |
| 22 | 3 | 3 | 3 | 3 | 0 | 0 | 1.5 | 13.5 |
| 23 | 1 | 2 | 2 | 1 | 0 | 1 | 0 | 7 |
| 24 | 1 | 2 | 1 | 0 | 0.5 | 0 | 0 | 4.5 |
| 25 | 3 | 3 | 3 | 3 | 0 | 0 | 1.5 | 13.5 |
| 26 | 2 | 3 | 1 | 3 | 0.5 | 0 | 0 | 8.5 |
| 27 | 2 | 3 | 2 | 2 | 0 | 1 | 0 | 10 |
| 28 | 3 | 3 | 3 | 2 | 0 | 0 | 1.5 | 12.5 |
| 29 | 3 | 2 | 3 | 1 | 0 | 1 | 0 | 10 |
| 30 | 3 | 3 | 3 | 1 | 0 | 0 | 1.5 | 11.5 |
| 1 | 1 | 1 | 0 | 0 | 0.5 | 0 | 0 | 2.5 |
| 2 | 0 | 0 | 0 | 0 | 0.5 | 0 | 0 | 0.5 |
| 3 | 0 | 0 | 0 | 0 | 0.5 | 0 | 0 | 0.5 |
| 4 | 1 | 1 | 0 | 1 | 0.5 | 0 | 0 | 3.5 |
| 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| 6 | 1 | 1 | 1 | 1 | 0.5 | 0 | 0 | 3.5 |
| 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | 0 | 0 | 0 | 0 | 0.5 | 0 | 0 | 0.5 |
| 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 | 1 | 1 | 0 | 0 | 0.5 | 0 | 0 | 0.5 |
| 15 | 1 | 1 | 1 | 1 | 0.5 | 0 | 0 | 5.5 |
| 16 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
| 17 | 0 | 1 | 0 | 0 | 0.5 | 0 | 0 | 1.5 |
| 18 | 0 | 0 | 0 | 0 | 0.5 | 0 | 0 | 0.5 |
| 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | 0 | 1 | 1 | 0 | 0.5 | 0 | 0 | 2.5 |
| 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 | 1 | 2 | 1 | 1 | 0.5 | 0 | 0 | 5.5 |
| 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 27 | 1 | 1 | 0 | 0 | 0.5 | 0 | 0 | 3 |
| 28 | 0 | 1 | 1 | 0 | 0.5 | 0 | 0 | 2.5 |
| 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| The comparison of total scores before and after treatment underwent by paired student’s t test. | ||||||||