28 October 2020>: Lab/In Vitro Research
Upregulation of Serine Proteinase Inhibitor Clade B Member 3 (SERPINB3) Expression by Stromal Cell-Derived Factor (SDF-1)/CXCR4/Nuclear Factor kappa B (NF-κB) Promotes Migration and Invasion of Gastric Cancer Cells
Jing Gong 1ABCDEF* , Yongxi Song 2AB* , Ling Xu 3ACEF , Xiaofang Che 3DEF , Kezuo Hou 3BC , Tianshu Guo 3BC , Yu Cheng 3ABG , Yunpeng Liu 3ADE* , Xiujuan Qu 3AG*DOI: 10.12659/MSM.927411
Med Sci Monit 2020; 26:e927411
Table 2 Correlations between CXCR4 expression and SERPINB3 levels in patients with primary gastric cancer.
CXCR4 | Cases (%) | SERPINB3 | |||
---|---|---|---|---|---|
Neg (%) | Pos (%) | R value | P value | ||
Neg (%) | 30 (31.3) | 19 (19.8) | 11 (11.5) | 0.222 | 0.029 |
Pos (%) | 66 (68.8) | 26 (11.5) | 40 (41.7) | ||
Cases (%) | 96 (100.0) | 45 (46.9) | 51 (53.1) |
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