Retracted: 28 Jul 2023 | Upregulation of Serine Proteinase Inhibitor Clade B Member 3 (SERPINB3) Expression by Stromal Cell-Derived Factor (SDF-1)/CXCR4/Nuclear Factor kappa B (NF-κB) Promotes Migration and Invasion of Gastric Cancer Cells

Jing Gong; Yongxi Song; Ling Xu; Xiaofang Che; Kezuo Hou; Tianshu Guo; Yu Cheng; Yunpeng Liu; Xiujuan Qu

doi:10.12659/MSM.927411

28 October 2020: Lab/In Vitro Research

Upregulation of Serine Proteinase Inhibitor Clade B Member 3 (SERPINB3) Expression by Stromal Cell-Derived Factor (SDF-1)/CXCR4/Nuclear Factor kappa B (NF-κB) Promotes Migration and Invasion of Gastric Cancer Cells

Jing Gong ^1ABCDEF* , Yongxi Song ^2AB* , Ling Xu ^3ACEF , Xiaofang Che ^3DEF , Kezuo Hou ^3BC , Tianshu Guo ^3BC , Yu Cheng ^3ABG , Yunpeng Liu ^3ADE* , Xiujuan Qu ^3AG*

DOI: 10.12659/MSM.927411

Med Sci Monit 2020; 26:e927411

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Table 3 Univariate and multivariate analysis of OS in GC patients with different characteristics.

Variable	Univariate			Multivariate
Variable	HR	95% CI	P value	HR	95% CI	P value
Age (	1.247	0.705–2.206	0.448
Gender (Male Female)	0.781	0.389–1.568	0.487
Lauren classification (others intestinal)	2.145	1.164–3.953	0.014^*	2.743	1.454–5.176	0.002^*
LN (positive negative)	4.704	1.686–13.128	0.003^*	2.933	1.027–8.382	0.045^*
T Stage (T4 T1/T2/T3)	1.893	0.941–3.810	0.074
CXCR4 (positive negative)	2.171	1.051–4.483	0.036^*
CXCR4 and SERPINB3 (positive other)	3.259	1.812–5.860	0.000^*	3.332	1.787–6.212	0.000^*
SERPINB3 (positive negative)	3.539	1.876–6.675	0.000^*
OS – overall survival; GC – gastric cancer; LN – lymph node metastasis. ^*

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Upregulation of Serine Proteinase Inhibitor Clade B Member 3 (SERPINB3) Expression by Stromal Cell-Derived Factor (SDF-1)/CXCR4/Nuclear Factor kappa B (NF-κB) Promotes Migration and Invasion of Gastric Cancer Cells

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