27 January 2021: Clinical Research
Percentage of Natural Killer (NK) Cells in Peripheral Blood Is Associated with Prognosis in Patients with Gastric Cancer: A Retrospective Study from a Single Center
Ming-zhi Xie 1BCE* , Ke Ding 2D* , Yan-ping Tang 3BDE* , Bang-li Hu 3CE , Ke-zhi Li 3CDE , Ji-lin Li 3BCD , Xin-qiang Liang 3AEG*DOI: 10.12659/MSM.927464
Med Sci Monit 2021; 27:e927464
Table 2 Risk factors for the prognosis in gastric cancer patients, with N0 and M0 as reference groups.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | 1.02 (1.00–1.04) | 0.019 | 1.01 (0.99–1.04) | 0.144 |
| Lymphocyte | 0.61 (0.42–0.88) | 0.009 | ||
| Albumin | 0.94 (0.91–0.96) | 1.01 (0.99–1.03) | 0.466 | |
| CEA | 1.00 (1.00–1.03) | 1.01 (0.93–1.07) | 0.405 | |
| CA125 | 1.00 (1.00–1.05) | 1.02 (1.00–1.04) | 0.180 | |
| CA153 | 1.02 (1.01–1.06) | 0.99 (0.97–1.02) | 0.901 | |
| CA199 | 1.00 (1.00–1.02) | |||
| NK | 0.92 (0.89–0.95) | |||
| CRP | 1.01 (1.07–1.02) | 1.00 (0.98–1.02) | 0.863 | |
| hsCRP | 1.16 (1.09–1.24) | |||
| NLR | 1.02 (1.06–1.05) | 0.013 | ||
| N stage | ||||
| N0 | – | – | ||
| N1 | 0.92 (0.56–1.50) | 0.740 | 1.03 (0.61–1.76) | 0.889 |
| N2 | 1.69 (1.07–2.66) | 0.022 | 1.15 (0.67–1.98) | 0.599 |
| N3 | 1.75 (1.05–2.75) | 0.029 | 2.63 (1.55–4.46) | 0.000 |
| M stage | ||||
| M0 | – | – | ||
| M1 | 4.89 (3.08–7.77) | |||