09 December 2020 : Clinical Research
Efficacy and Safety of Image-Guided Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy Combined with Paclitaxel Liposomes and Cisplatin for Locally Advanced Stage IIB–IIIB Cervical Cancer: A Retrospective Study at a Single Center
Meihua Xie1ABE, Xiuxiu Ding1BCE, Aiyu Chen1CF, Huiqin Xiao1DF, Xiaoye Wang1BD, Youhong Wang1AC, Huan Zhang1ADG*DOI: 10.12659/MSM.927563
Med Sci Monit 2020; 26:e927563
Table 1 Baseline demographic and clinical characteristics of the studied patients.
| Parameters | IMRT group (n=63) | VMAT group (n=63) | P-value |
|---|---|---|---|
| Age | 54.36±10.03 | 52.91±9.67 | 0.410 |
| Course of disease (years) | 3.2±0.7 | 3.4±0.8 | 0.138 |
| Histology | 0.528 | ||
| Squamous cell carcinoma | 48 (79.2%) | 53 (83.3%) | |
| Adenocarcinoma | 10 (16.7%) | 7 (14.6%) | |
| Adenosquamous carcinoma | 5 (4.1%) | 3 (2.1%) | |
| Tumor size (cm) | 3.7±1.2 | 3.5±1.0 | 0.088 |
| FIGO stage | 0.534 | ||
| II B | 22 (18.8%) | 28 (22.9%) | |
| III A | 27 (22.9%) | 24 (29.2%) | |
| III B | 14 (56.3%) | 11 (47.9%) | |
| Differentiation degree | 0.771 | ||
| High | 16 (31.3%) | 18 (27.1%) | |
| Moderate | 29 (43.7%) | 25 (54.2%) | |
| Low | 18 (25.0%) | 20 (18.7%) | |
| KPS score | 0.367 | ||
| 80–90 | 39 (43.7%) | 34 (54.2%) | |
| 70–80 | 24 (25.0%) | 29 (18.7%) | |
| IMRT –intensity-modulated radiation therapy; VMAT – volumetric modulated arc therapy; FIGO – Federation of Gynecology and Obstretics; KPS – Karnofsky Performance Status. | |||