21 December 2020 : Clinical Research
Retrospective Study of Clinical Features of COVID-19 in Inpatients and Their Association with Disease Severity
Hao Wang1AE, Yang Xing2CDEF, Xiaohong Yao3BD, Yang Li1C, Jietao Huang1CD, Jun Tang1BF, Shasha Zhu1CD, Ying Zhang1EG, Jun Xiao1G*DOI: 10.12659/MSM.927674
Med Sci Monit 2020; 26:e927674
Table 1 Demographic data and clinical presentations of patients with COVID-19.
| Total (N=61) | Common group (N=37) | Severe group (N=24) | P value | |
|---|---|---|---|---|
| Age, median(IQR%), y | 53 (40–62) | 51 (40–62) | 54 (47–66) | 0.315 |
| Sex | ||||
| Female | 30 (49.2%) | 21 (56.8%) | 9 (37.5%) | 0.142 |
| Male | 31 (50.8%) | 16 (43.2%) | 15 (62.5%) | |
| Comorbidities | 18 (29.5%) | 8 (21.6%) | 10 (41.7%) | 0.094 |
| Hypertension | 12 (19.7%) | 5 (13.5%) | 7 (29.2%) | 0.133 |
| Diabetes | 6 (9.8%) | 3 (8.1%) | 3 (12.5%) | 0.902 |
| Cardiovascular disease | 4 (6.6%) | 2 (5.4%) | 2 (8.3%) | 1 |
| Malignancy | 1 (1.6%) | 1 (2.7%) | 0 | 0.315 |
| Chronic liver disease | 1 (1.6%) | 1 (2.7%) | 0 | 0.315 |
| Signs and symptoms | ||||
| Fever | 49 (80.3%) | 30 (81.1%) | 19 (79.2%) | 0.854 |
| Cough | 37 (60.7%) | 20 (54.1%) | 17 (70.8%) | 0.19 |
| Fatigue | 33 (54.1%) | 19 (54.1%) | 14 (58.3%) | 0.593 |
| Dyspnea | 21 (34.4%) | 7 (18.9%) | 14 (58.3%) | 0.002 |
| Myalgia | 15 (24.6%) | 10 (27.0%) | 5 (20.8%) | 0.583 |
| Dizziness | 12 (19.7%) | 7 (18.9%) | 5 (20.8%) | 1 |
| Headache | 11 (18.0%) | 8 (21.6%) | 3 (12.5%) | 0.572 |
| Diarrhea | 4 (6.6%) | 2 (5.4%) | 2 (8.3%) | 1 |
| Heart rate, median (IQR%), bpm | 85 (78–94) | 85 (75–90) | 89 (79–101) | 0.169 |
| Respiratory rate, median (IQR%) | 20 (20–21) | 20 (20–20) | 21 (20–29) | <0.001 |
| Mean arterial pressure, median (IQR%), mmHg | 93 (87–103) | 91 (85–103) | 99 (92–109) | 0.024 |