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21 December 2020: Clinical Research

Retrospective Study of Clinical Features of COVID-19 in Inpatients and Their Association with Disease Severity

Hao Wang 1AE* , Yang Xing 2CDEF* , Xiaohong Yao 3BD , Yang Li 1C , Jietao Huang 1CD , Jun Tang 1BF , Shasha Zhu 1CD , Ying Zhang 1EG* , Jun Xiao 1G*

DOI: 10.12659/MSM.927674

Med Sci Monit 2020; 26:e927674

Table 3 Results of logistic analysis of risk factors for disease severity.

VariablesUnivariate analysisMultivariate analysis
OR95% CIPOR95% CIP
Sex (Male Female)0.4570.160–1.3080.145
Age (1.250.426–3.6640.684
Respiratory rate (>20 breaths/min ≤20 breaths/min)0.1350.016–1.1480.067
WBC (0.3870.114–1.3090.127
Neutrophil count (––––––1
Lymphocytes (0.1170.036–0.3800.0940.009–1.0320.053
Platelet count (0.1390.015–1.3290.087
Albumin (0.580.185–1.8190.35
Aspartate aminotransferase (≤40 U/L >40 U/L)0.5240.074–3.7030.517
Urea (≤8 mmol/L >8 mmol/L)––––––0.999
Creatinine (≤97 μmol/L >97 μmol/L)0.20.020–2.0490.175
D-dimer (>1.5 ng/mL ≤1.5 ng/mL)0.490.117–2.0560.33
Prothrombin time (>13.5 s ≤13.5 s)0.250.079–0.7910.0180.0140.001–0.3410.009
Creatine kinase isoenzymes (>24 U/L ≤24 U/L)0.2020.020–2.0770.179
Lactate dehydrogenas (≥250 U/L0.1850.052–0.6580.009
C-reactive protein (>5 mg/L ≤5 mg/L)0.150.042–0.5330.0030.0280.002–0.5260.017
Procalcitonin (>0.5 μg/L vs. ≤0.5 μg/L)0.2830.047–1.7120.169
NLR (>4.4 ≤4.4)0.0940.027–0.328
LMR (1.5650.093–26.2790.756
PLR (>200.8 ≤200.8)0.1120.032–0.3870.001
MPVLR (>8.9 ≤8.9)0.080.023–0.2760.0260.002–0.3490.006
CAR (>0.66 ≤0.66)0.1380.043–0.4380.001

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750