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01 February 2021: Clinical Research

Presence of Metabolic Syndrome and Thyroid Nodules in Subjects with Colorectal Polyps

Yue Yu ABCDEF , Jiansheng Wu ADE*

DOI: 10.12659/MSM.927935

Med Sci Monit 2021; 27:e927935

Table 1 Baseline features and independent risk factors in colorectal polyps.

Basic informationPolyps (1379)Non-polyp (3135)P valueUnivariate analysisMultivariate analysis
OR (95%CI)POR (95%CI)P
Age (years)50 (44–57)45 (39–52)0.0002.311 (2.008–2.661)0.0001.049 (1.042–1.057)0.000
Sex (Male)1033(74.9)1767(56.4)0.0001.048 (1.041–1.055)0.0001.767 (1.398–2.233)0.000
BMI (kg/m)24.5(±3.1)23.3 (21.2–25.5)0.0001.114 (1.091–1.137)0.0001.049 (1.021–1.077)0.000
TC (mmol/L)5.31 (4.68–6.00)5.2 (4.6–5.9)0.0031.082 (1.020–1.147)0.0091.138 (0.886–1.462)0.312
TG (mmol/L)1.61 (1.10–2.38)1.32 (0.94–2.05)0.0001.094 (1.049–1.140)0.0000.905 (0.815–1.004)0.060
HDL-C (mmol/L)1.18 (1.02–1.40)1.27 (1.08–1.51)0.0000.446 (0.363–0.549)0.0000.689 (0.476–0.996)0.048
LDL-C (mmol/L)3.20 (2.67–3.79)3.10 (2.61–3.67)0.0011.128 (1.047–1.215)0.0010.885 (0.668–1.172)0.394
TSH (mIU/L)1.54 (1.10–2.22)1.64 (1.14–2.41)0.0050.925 (0.878–0.975)0.0040.954 (0.909–1.001)0.053
FT (pmol/L)11.1 (10.2–12.3)11.2 (10.2–12.3)0.5620.997 (0.972–1.022)0.787
FT (pmol/L)5.0 (4.6–5.4)5.0 (4.5–5.4)0.9711.016 (0.956–1.080)0.617
FPG (mmol/L)4.8 (4.3–5.2)4.7 (4.2–5.1)0.0001.182 (1.120–1.248)0.0001.029 (0.968–1.093)0.357
UA (mmol/L)353 (298–415)331 (271–391)0.0001.003 (1.002–1.004)0.0001.000 (0.999–1.001)0.551
Scr (umol/L)70 (60–78)65 (55–75)0.0001.020 (1.016–1.020)0.0001.000 (0.993–1.007)0.929
ALT (U/L)24 (17–37)22 (16–33)0.0001.004 (1.002–1.006)0.0011.001 (0.996–1.005)0.788
AST (U/L)25 (20–31)24 (20–29)0.0001.005 (1.002–1.009)0.0061.000 (0.993–1.007)0.959
Smoking n (%)542(39.3)738(23.5)0.0002.103 (1.836–2.410)0.0001.670 (1.412–1.976)0.000
Alcohol n (%)601(43.6)1050(33.5)0.0001.534 (1.347–1.746)0.0000.998 (0.849–1.172)0.976
TNs n (%)542(39.3)1035(33.0)0.0001.314 (1.152–1.498)0.0001.221 (1.005–1.413)0.007
MS n (%)277(20.1)340(10.8)0.0002.066 (1.738–2.457)0.0001.343 (1.082–1.665)0.007
ALT – alanine aminotransferase; AST – aspartate aminotransferase; BMI – body mass index; FPG – fasting plasma glucose; FT – free triiodothyronine; FT – free thyroxine; HDL-C – high-density lipoprotein cholesterol; LDL-C – low-density lipoprotein cholesterol; MS – metabolic syndrome; OR – odds ratio; Scr – serum creatinine; TC – total cholesterol; TG – triglyceride; TNs – thyroid nodules; TSH – thyrotropin; UA – uric acid.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750