01 February 2021>: Clinical Research
Presence of Metabolic Syndrome and Thyroid Nodules in Subjects with Colorectal Polyps
Yue Yu ABCDEF , Jiansheng Wu ADE*DOI: 10.12659/MSM.927935
Med Sci Monit 2021; 27:e927935
Table 1 Baseline features and independent risk factors in colorectal polyps.
Basic information | Polyps (1379) | Non-polyp (3135) | P value | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|---|---|
OR (95%CI) | P | OR (95%CI) | P | ||||
Age (years) | 50 (44–57) | 45 (39–52) | 0.000 | 2.311 (2.008–2.661) | 0.000 | 1.049 (1.042–1.057) | 0.000 |
Sex (Male) | 1033(74.9) | 1767(56.4) | 0.000 | 1.048 (1.041–1.055) | 0.000 | 1.767 (1.398–2.233) | 0.000 |
BMI (kg/m) | 24.5(±3.1) | 23.3 (21.2–25.5) | 0.000 | 1.114 (1.091–1.137) | 0.000 | 1.049 (1.021–1.077) | 0.000 |
TC (mmol/L) | 5.31 (4.68–6.00) | 5.2 (4.6–5.9) | 0.003 | 1.082 (1.020–1.147) | 0.009 | 1.138 (0.886–1.462) | 0.312 |
TG (mmol/L) | 1.61 (1.10–2.38) | 1.32 (0.94–2.05) | 0.000 | 1.094 (1.049–1.140) | 0.000 | 0.905 (0.815–1.004) | 0.060 |
HDL-C (mmol/L) | 1.18 (1.02–1.40) | 1.27 (1.08–1.51) | 0.000 | 0.446 (0.363–0.549) | 0.000 | 0.689 (0.476–0.996) | 0.048 |
LDL-C (mmol/L) | 3.20 (2.67–3.79) | 3.10 (2.61–3.67) | 0.001 | 1.128 (1.047–1.215) | 0.001 | 0.885 (0.668–1.172) | 0.394 |
TSH (mIU/L) | 1.54 (1.10–2.22) | 1.64 (1.14–2.41) | 0.005 | 0.925 (0.878–0.975) | 0.004 | 0.954 (0.909–1.001) | 0.053 |
FT (pmol/L) | 11.1 (10.2–12.3) | 11.2 (10.2–12.3) | 0.562 | 0.997 (0.972–1.022) | 0.787 | – | – |
FT (pmol/L) | 5.0 (4.6–5.4) | 5.0 (4.5–5.4) | 0.971 | 1.016 (0.956–1.080) | 0.617 | – | – |
FPG (mmol/L) | 4.8 (4.3–5.2) | 4.7 (4.2–5.1) | 0.000 | 1.182 (1.120–1.248) | 0.000 | 1.029 (0.968–1.093) | 0.357 |
UA (mmol/L) | 353 (298–415) | 331 (271–391) | 0.000 | 1.003 (1.002–1.004) | 0.000 | 1.000 (0.999–1.001) | 0.551 |
Scr (umol/L) | 70 (60–78) | 65 (55–75) | 0.000 | 1.020 (1.016–1.020) | 0.000 | 1.000 (0.993–1.007) | 0.929 |
ALT (U/L) | 24 (17–37) | 22 (16–33) | 0.000 | 1.004 (1.002–1.006) | 0.001 | 1.001 (0.996–1.005) | 0.788 |
AST (U/L) | 25 (20–31) | 24 (20–29) | 0.000 | 1.005 (1.002–1.009) | 0.006 | 1.000 (0.993–1.007) | 0.959 |
Smoking n (%) | 542(39.3) | 738(23.5) | 0.000 | 2.103 (1.836–2.410) | 0.000 | 1.670 (1.412–1.976) | 0.000 |
Alcohol n (%) | 601(43.6) | 1050(33.5) | 0.000 | 1.534 (1.347–1.746) | 0.000 | 0.998 (0.849–1.172) | 0.976 |
TNs n (%) | 542(39.3) | 1035(33.0) | 0.000 | 1.314 (1.152–1.498) | 0.000 | 1.221 (1.005–1.413) | 0.007 |
MS n (%) | 277(20.1) | 340(10.8) | 0.000 | 2.066 (1.738–2.457) | 0.000 | 1.343 (1.082–1.665) | 0.007 |
ALT – alanine aminotransferase; AST – aspartate aminotransferase; BMI – body mass index; FPG – fasting plasma glucose; FT – free triiodothyronine; FT – free thyroxine; HDL-C – high-density lipoprotein cholesterol; LDL-C – low-density lipoprotein cholesterol; MS – metabolic syndrome; OR – odds ratio; Scr – serum creatinine; TC – total cholesterol; TG – triglyceride; TNs – thyroid nodules; TSH – thyrotropin; UA – uric acid. |