12 November 2020>: Clinical Research
Red Blood Cell Distribution Width-to-Platelet Ratio and Other Laboratory Indices Associated with Severity of Histological Hepatic Fibrosis in Patients with Autoimmune Hepatitis: A Retrospective Study at a Single Center
Xu Li 1BCE , Hongqin Xu 12CD , Pujun Gao 1AG*DOI: 10.12659/MSM.927946
Med Sci Monit 2020; 26:e927946
Table 3 Diagnostic performance of serum models of advanced autoimmune hepatitis-related fibrosis.
Variables | AUROC | (95% CI) | Cut-off | Se (%) | Sp (%) | Correct classified (%) |
---|---|---|---|---|---|---|
RPR (ln) | 0.821 | 0.713–0.928 | −2.313 | 77.8 | 77.8 | 77.8 |
RLR | 0.705 | 0.571–0.839 | 10.747 | 70.4 | 75.6 | 73.6 |
AAR | 0.646 | 0.520–0.772 | 0.761 | 92.6 | 40.0 | 59.7 |
APRI | 0.579 | 0.446–0.711 | 1.896 | 74.1 | 48.9 | 58.3 |
FIB-4 | 0.702 | 0.579–0.826 | 5.104 | 63.0 | 73.3 | 69.4 |
GPR | 0.599 | 0.463–0.735 | 0.769 | 77.8 | 46.7 | 58.3 |
NLR | 0.637 | 0.510–0.764 | 1.162 | 88.9 | 42.2 | 59.7 |
RDW | 0.682 | 0.549–0.816 | 15.95 | 48.1 | 86.7 | 72.2 |
AUROC – area under the receiver operating characteristic curve; 95% CI – 95% confidence interval; Se – sensitivity; Sp – specificity. Cut-offs were established by maximizing the sums of sensitivity and specificity. |