04 February 2021: Database Analysis
High Expression of the Component 3a Receptor 1 (C3AR1) Gene in Stomach Adenocarcinomas Infers a Poor Prognosis and High Immune-Infiltration Levels
Haibo Yang 1ABCDF , Lin Li 2BD , Xiaoyu Liu 1B , Yu Zhao 1ADG*DOI: 10.12659/MSM.927977
Med Sci Monit 2021; 27:e927977
Table 1 Biological processes of C3AR1 were analyzed by GSEA software.
| Name | SIZE | ES | NES | NOM p-val | FDR q-val |
|---|---|---|---|---|---|
| GO_INFLAMMATORY_RESPONSE | 442 | 0.665513 | 2.568941 | 0 | 0 |
| GO_IMMUNE_EFFECTOR_PROCESS | 449 | 0.654583 | 2.5537 | 0 | 0 |
| GO_CYTOKINE_PRODUCTION | 118 | 0.719826 | 2.551827 | 0 | 0 |
| GO_LEUKOCYTE_MIGRATION | 256 | 0.678578 | 2.550392 | 0 | 0 |
| GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 364 | 0.649705 | 2.537406 | 0 | 0 |
| GO_ACTIVATION_OF_IMMUNE_RESPONSE | 388 | 0.682517 | 2.526013 | 0 | 0 |
| GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 418 | 0.606066 | 2.525585 | 0 | 0 |
| GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 439 | 0.647561 | 2.517916 | 0 | 0 |
| GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | 360 | 0.645124 | 2.514322 | 0 | 0 |
| GO_REGULATION_OF_CYTOKINE_SECRETION | 142 | 0.701544 | 2.498589 | 0 | 0 |
| GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 293 | 0.633304 | 2.492779 | 0 | 0 |
| GO_LEUKOCYTE_MEDIATED_IMMUNITY | 157 | 0.670396 | 2.48643 | 0 | 0 |
| GO_RESPONSE_TO_INTERFERON_GAMMA | 139 | 0.77279 | 2.483442 | 0 | 0 |
| GO_LEUKOCYTE_ACTIVATION | 409 | 0.667228 | 2.480178 | 0 | 0 |
| GO_REGULATION_OF_CELL_ACTIVATION | 451 | 0.654573 | 2.479348 | 0 | 0 |
| GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | 159 | 0.680143 | 2.477039 | 0 | 0 |
| GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 361 | 0.609162 | 2.474501 | 0 | 0 |
| GO_MYELOID_LEUKOCYTE_MIGRATION | 96 | 0.707282 | 2.470155 | 0 | 0 |
| GO_REGULATION_OF_INFLAMMATORY_RESPONSE | 285 | 0.627035 | 2.469305 | 0 | 0 |
| GO_LEUKOCYTE_CHEMOTAXIS | 114 | 0.724023 | 2.469249 | 0 | 0 |
| GO_GRANULOCYTE_MIGRATION | 72 | 0.743939 | 2.464845 | 0 | 0 |
| GO_REGULATION_OF_INNATE_IMMUNE_RESPONSE | 353 | 0.649503 | 2.462347 | 0 | 0 |
| GO_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA | 117 | 0.786396 | 2.456372 | 0 | 0 |
| GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 201 | 0.689642 | 2.45446 | 0 | 0 |
| GO_ADAPTIVE_IMMUNE_RESPONSE | 251 | 0.730522 | 2.450656 | 0 | 0 |
| GO_MYELOID_LEUKOCYTE_ACTIVATION | 95 | 0.741534 | 2.45024 | 0 | 0 |
| GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | 156 | 0.705238 | 2.444989 | 0 | 0 |
| GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 156 | 0.686433 | 2.441367 | 0 | 0 |
| GO_REGULATION_OF_T_CELL_PROLIFERATION | 143 | 0.697275 | 2.440364 | 0 | 0 |
| GO_RESPONSE_TO_BACTERIUM | 499 | 0.571084 | 2.435284 | 0 | 0 |
| SIZE – number of genes; ES – enrichment score; NES – normalized enrichment scores; NOM p-val – normalized P-value; FDR q-val – q-value of false discovery rate. We generally assume that the absolute value of NES >1.0, NOM P-val | |||||