26 December 2020 : Database Analysis
Laryngeal Squamous Cell Carcinoma: Potential Molecular Mechanism and Prognostic Signature Based on Immune-Related Genes
Bin-Yu Mo1BCEF, Guo-Sheng Li2BCEF, Su-Ning Huang3DEF, Zhu-Xin Wei2DEF, Ya-Si Su4DEF, Wen-Bin Dai4ADG, Lin Ruan2ADEG*DOI: 10.12659/MSM.928185
Med Sci Monit 2020; 26:e928185
Table 2 Immune-related differentially expressed genes (IRDEGs) included in the signature.
| IRDEGs of signature | Log2 (fold change) | Multivariate Cox regression analyses | Coefficient in signature | |
|---|---|---|---|---|
| HR | 95% CI of HR | |||
| BTC | −2.181 | 2.267 | 1.089–4.718 | 0.818 |
| FGF19 | 8.111 | 1.383 | 0.996–1.922 | 0.325 |
| GAST | 5.928 | 1.668 | 0.955–2.912 | 0.511 |
| IGHV3–7 | 2.533 | 0.720 | 0.502–1.033 | −0.328 |
| IL13RA2 | 2.413 | 2.100 | 1.230–3.584 | 0.742 |
| RBP1 | 2.596 | 23.026 | 3.416–155.202 | 3.137 |
| RORC | −2.691 | 0.344 | 0.145–0.817 | −1.068 |
| TUBB3 | 2.400 | 5.835 | 1.380–24.671 | 1.764 |
| UCN | 2.183 | 0.314 | 0.141–0.700 | −1.160 |
| HR – hazard ratio; CI – confidence interval. | ||||