03 March 2021 : Animal Research
A Network Pharmacology Study of the Molecular Mechanisms of Hypericum japonicum in the Treatment of Cholestatic Hepatitis with Validation in an Alpha-Naphthylisothiocyanate (ANIT) Hepatotoxicity Rat Model
Sen Ling Feng1ACE, Jing Zhang2BCEF, Hongliu Jin1BC, Wen Ting Zhu1BC, Zhongwen Yuan1ABCDEFG*DOI: 10.12659/MSM.928402
Med Sci Monit 2021; 27:e928402
Table 3 The node characteristic parameters of the main active ingredients in compound-target network.
| MOL ID | Component name | Degree | Betweenness | Closeness |
|---|---|---|---|---|
| MOL000098 | Quercetin | 74 | 0.756382 | 0.643678 |
| MOL000422 | Kaempferol | 26 | 0.100813 | 0.408759 |
| MOL007879 | Tetramethoxyluteolin | 17 | 0.117672 | 0.386207 |






