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14 January 2021: Clinical Research

Comparison of Rocuronium with Succinylcholine for Rapid Sequence Induction Intubation in the Emergency Department: A Retrospective Study at a Single Center in China

Gui Li 1ABF , Lin Cheng 2DEF* , Jianke Wang 1ADF

DOI: 10.12659/MSM.928462

Med Sci Monit 2021; 27:e928462

Table 1 Demographical, clinical, and anesthetic conditions of the enrolled patients at the Emergency Department.

Neuromuscular blocking agent usedSuccinylcholineRocuronium
Patients included in analysis141126P value
SexMale95 (67)73 (58)0.128
Female46 (33)53 (42)
Age (y)Minimum18180.344
Body mass index (kg/m)24.12±2.2224.41±1.450.213
Reason for intubationShock18 (13)17 (13)0.998
Trauma22 (16)21 (17)
Coma due to neurological disease37 (26)33 (26)
Coma due to poisoning31 (22)25 (20)
Overdoses17 (12)16 (13)
Dyspnea16 (11)14 (11)
Glasgow Coma Scale scoreMinimum330.828
Heart rate (beats/min)105±11102±150.062
Arterial diastolic pressure (mmHg)115 (82)101 (80)0.876
26 (18)25 (20)
Arterial systolic pressure (mmHg)109 (77)88 (70)0.211
≥14032 (23)38 (30)
% Peripheral oxygen saturation94.51±4.5594.01±4.010.344
Total etomidate administered (mg)22.12±4.15 (n=115)21.15±4.11 (n=107)0.057
Total ketamine administered (mg)39±4 (n=26)41±5 (n=19)0.143
Total propofol administered (mg)527±21531±250.197
Cancer history9 (6)2 (2)0.065
Cardiac disease history15 (11)7 (6)0.181
Renal disease history4 (3)11 (9)0.059
Patient position during intubationLying on a stretcher87 (62)79 (63)0.897
Lying on a bed54 (38)47 (37)
Descriptive data are demonstrated as frequency (percentage) and numerical and ordinal data are demonstrated as mean±SD. Two-tailed unpaired test was performed for numerical and ordinal data and the Fischer exact test was performed for descriptive data. All results were considered significant if the value was less than 0.05.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750