22 February 2021>: Clinical Research
Fractional Exhaled Nitric Oxide (FeNO) Integrating Airway Hyperresponsiveness (AHR) Examination Promotes Etiologic Diagnosis and Treatment for Children with Chronic Cough
Haiyan Zhu 1BCDEF , Chuangli Hao 2BCDE , Xingmei Yu 2BCDF , Rongrong Zhang 1BCD , Wendi Zhou 1BCF , Xingzhen Sun 1BCF , Yufang Yuan 1BCF , Zhaofang Tian 1ABDEG*DOI: 10.12659/MSM.928502
Med Sci Monit 2021; 27:e928502
Table 1 Comparisons for initial diagnosis of fractional exhaled nitric oxide (FeNO) and other parameters in children with chronic cough for different etiologies (χ±s).
Parameters | CVA group (n=45) | UACS group (n=53) | PIC group (n=20) | F/χ2 | P |
---|---|---|---|---|---|
FeNO | 35±14* | 17±8 | 19±8 | 20.810 | 0.000 |
EOS in sputum (%, median) | 6.5 (6)* | 0.5 (1) | 0.5 (1.5) | 6.688 | 0.001 |
Cough symptom score | 3.5±0.7 | 3.2±0.7 | 3.5±1.0 | 2.224 | 0.090 |
CVA – cough-variant asthma; UACS – upper-airway cough syndrome; PIC – post-infection cough. * # |