22 February 2021 : Clinical Research
Fractional Exhaled Nitric Oxide (FeNO) Integrating Airway Hyperresponsiveness (AHR) Examination Promotes Etiologic Diagnosis and Treatment for Children with Chronic Cough
Haiyan Zhu1BCDEF, Chuangli Hao2BCDE, Xingmei Yu2BCDF, Rongrong Zhang1BCD, Wendi Zhou1BCF, Xingzhen Sun1BCF, Yufang Yuan1BCF, Zhaofang Tian1ABDEG*DOI: 10.12659/MSM.928502
Med Sci Monit 2021; 27:e928502
Table 1 Comparisons for initial diagnosis of fractional exhaled nitric oxide (FeNO) and other parameters in children with chronic cough for different etiologies (χ±s).
| Parameters | CVA group (n=45) | UACS group (n=53) | PIC group (n=20) | F/χ2 | P |
|---|---|---|---|---|---|
| FeNO | 35±14* | 17±8 | 19±8 | 20.810 | 0.000 |
| EOS in sputum (%, median) | 6.5 (6)* | 0.5 (1) | 0.5 (1.5) | 6.688 | 0.001 |
| Cough symptom score | 3.5±0.7 | 3.2±0.7 | 3.5±1.0 | 2.224 | 0.090 |
| CVA – cough-variant asthma; UACS – upper-airway cough syndrome; PIC – post-infection cough. * # | |||||