22 February 2021: Clinical Research
Fractional Exhaled Nitric Oxide (FeNO) Integrating Airway Hyperresponsiveness (AHR) Examination Promotes Etiologic Diagnosis and Treatment for Children with Chronic Cough
Haiyan Zhu 1BCDEF , Chuangli Hao 2BCDE , Xingmei Yu 2BCDF , Rongrong Zhang 1BCD , Wendi Zhou 1BCF , Xingzhen Sun 1BCF , Yufang Yuan 1BCF , Zhaofang Tian 1ABDEG*DOI: 10.12659/MSM.928502
Med Sci Monit 2021; 27:e928502
Table 2 Comparative analysis of pulmonary function indexes in children with chronic cough for the different etiologies (χ±s).
| Parameters | CVA group (n=45) | UACS group (n=53) | PIC group (n=20) | F | P |
|---|---|---|---|---|---|
| FEV1% pred | 93±14 | 99±10 | 94±10 | 1.918 | 0.136 |
| FEV1/FVC | 104±10 | 104±17 | 102±3 | 0.169 | 0.917 |
| FEF25 | 85±21 | 92±14 | 93±13 | 2.973 | 0.035 |
| FEF50 | 80±22 | 96±18 | 88±11 | 5.649 | 0.001 |
| FEF75 | 76±29 | 95±26 | 86±17 | 3.400 | 0.021 |
| CVA – cough-variant asthma; UACS – upper-airway cough syndrome; PIC – post-infection cough; FEV1 – forced expiratory volume in 1 s; FVC – forced vital capacity; FEF25, 50, 75 – 25%, 50%, 75% forced expiratory flow. | |||||