A Single-Center Prospective Study of 116 Women with Osteoporosis Treated with Zoledronic Acid Monitored by Electrocardiography for the Development of Cardiac Arrhythmia During the Acute Phase in China

12 March 2021 : Clinical Research

HuaFeng Zhuang^1BCE*, YiZhong Li^1ABC, JinKuang Lin^1BCD, XueDong Yao^1CDF, YanYu Xie^2BCF, PeiWen Wang^1BDF, Hao Xu^1CDF

DOI: 10.12659/MSM.928637

Med Sci Monit 2021; 27:e928637

Background Material and Methods Results Discussion Conclusions References

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Table 2 Electrocardiogram findings of patients before and after zoledronate administration.

	Before zoledronate adminstration	After zoledronate adminstration	p
Normal ECG	47	35	0.099
Abnormal ECG	69	81	0.099
Sinus arrhythmia	13	13
Sinusal tachycardia	2	9
Sinusal bradycardia	9	2
Atrial premature	6	5
Ventricular premature	1	3
Atrial fibrillation/flutter	0	1
branch block	2	4
Atrioventricular block	0	1
Left ventricular hypertrophy	6	6
ST or T Wave change	30	37
ECG – electrocardiograph;

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