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02 December 2020: Clinical Research

A Retrospective Study on the Effects of Convalescent Plasma Therapy in 24 Patients Diagnosed with COVID-19 Pneumonia in February and March 2020 at 2 Centers in Wuhan, China

Shuang Huang C* , Changxin Shen B* , Chengliang Xia F , Xiaoxing Huang C , Yourong Fu A , Li Tian E*

DOI: 10.12659/MSM.928755

Med Sci Monit 2020; 26:e928755

Table 3 The laboratory findings before and after convalescent plasma transfusion in 14 patients with COVID-19 pneumonia who had an effective response to this treatment.

Laboratory indicatorsNormal rangeBefore CP transfusionAfter CP transfusionP values
WBC, 10/L3.5–9.59.28 (6.91–10.96)8.84 (7.16–11.37)0.982
Lymphocyte, 10/L1.1–3.20.80 (0.58–0.91)1.12 (0.87–2.11)0.004*
CRP, mg/L0–464.14 (32.85–96.10)26.08 (8.34–42.09)0.008*
PCT, ng/ml0–0.050.55 (0.19–1.71)0.31 (0.09–0.48)0.273
ALT, IU/L7–4530.50 (22.50–64.50)24.50 (12.00–39.25)0.175
AST, IU/L13–3537.50 (25.00–55.25)28.00 (22.50–40.00)0.375
Urea, mmol/L3.1–8.87.90 (5.73–11.93)7.45 (3.85–15.53)0.581
WBC – white blood cell; CRP – high-sensitivity C-reactive protein; PCT – procalcitonin; ALT – alanine aminotransferase; AST – aspartate transaminase; urea – urea nitrogen.
* Indicated statistical significance (

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750