25 December 2020: Clinical Research
Elevated CA-125 Level and ER-Negative as Prognostic Factors for Ovarian Metastasis in Patients with Endometrial Cancer: A Retrospective Cohort Study
Xiaoting Ling 1ABCE* , Zheyu Zheng 2ABCE* , Jing Xu 1C , Guocai Xu 1F , Hui Zhou 1CD , Zhongqiu Lin 1F , Yangyang Li 3BDE , Jinxiao Liang 1AG* , Huaiwu Lu 1AD*DOI: 10.12659/MSM.928826
Med Sci Monit 2020; 26:e928826
Table 2 Univariate analyses of clinical pathological risk factors for ovarian metastasis.
| Variables | Ovarian metastasis | P value | |
|---|---|---|---|
| Positive | Negative | ||
| Histological type | |||
| Nonendometrioid | 7 | 59 | 0.065 |
| Endometrioid | 25 | 474 | |
| Type | |||
| Type II | 12 | 98 | 0.001 |
| Type I | 20 | 435 | |
| Tubal involvement | |||
| Yes | 17 | 26 | 0 |
| No | 15 | 506 | |
| Myometrial invasion | |||
| ≥1/2 | 19 | 95 | 0 |
| 13 | 438 | ||
| LVSI | |||
| Yes | 9 | 51 | 0.001 |
| No | 23 | 482 | |
| Lymph node metastasis | |||
| Yes | 7 | 50 | 0.023 |
| No | 25 | 483 | |
| Cervical extension | |||
| Yes | 12 | 53 | 0 |
| No | 20 | 480 | |
| Parametrial involvement | |||
| Yes | 10 | 11 | 0 |
| No | 22 | 522 | |
| Vaginal involvement | |||
| Yes | 2 | 4 | 0.003 |
| No | 30 | 529 | |
| Positive peritoneal washings/ascites | |||
| Yes | 3 | 7 | 0.001 |
| No | 29 | 526 | |
| Longest tumor diameter | |||
| 6 | 137 | 0.017 | |
| 2~5 | 8 | 226 | |
| 5 | 18 | 170 | |
| Age | |||
| ≥50 | 21 | 370 | 0.652 |
| 11 | 163 | ||
| Menopause | |||
| Yes | 21 | 255 | 0.051 |
| No | 11 | 278 | |