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01 March 2021: Database Analysis

Comparison of Prognostic Value Among 4 Risk Scores in Patients with Acute Coronary Syndrome: Findings from the Improving Care for Cardiovascular Disease in China-ACS (CCC-ACS) Project

Jieleng Huang 12BCEF* , Xuebiao Wei 23CD* , Yu Wang 2BE , Mei Jiang 2BC , Yingwen Lin 2BC , Zedazhong Su 2BC , Peng Ran 2B , Yingling Zhou 2G , Jiyan Chen 2AG , Danqing Yu 12AG*

DOI: 10.12659/MSM.928863

Med Sci Monit 2021; 27:e928863

Table 2 ROC Comparison for death, MACEs, bleeding, according to the C-ACS, ACEF, AGEF, and GRACE risk score.

NST-ACSSTEMI
Comparison (A vs B)AUC-A%AUC-B%ΔAUC%P valueAUC-A%AUC-B%ΔAUC%P value
DeathC-ACS vs ACEF76.682.76.1 (2.0 to 10.0)0.00376.782.76.0 (3.4 to 8.7)
C-ACS vs AGEF76.683.26.6 (2.8 to 10.4)76.784.57.8 (5.4 to10.2)
C-ACS vs GRACE76.685.38.7 (5.4 to 12.0)76.781.95.2 (3.5 to 7.1)
ACEF vs AGEF82.783.20.5 (−1.3 to 2.4)0.55982.784.51.8 (0.3 to 3.1)0.014
ACEF vs GRACE82.785.32.6 (−0.3 to 5.7)0.08282.781.90.8 (−1.5 to 3.1)0.486
AGEF vs GRACE83.285.32.1 (−0.7 to 4.9)0.14084.581.92.6 (0.6 to 4.5)0.012
MACEsC-ACS vs ACEF75.177.72.6 (1.2 to 4.0)71.171.90.8 (−0.4 to 1.8)0.190
C-ACS vs AGEF75.177.62.5 (1.1 to 3.9)71.172.11.0 (−0.2 to 2.0)0.094
C-ACS vs GRACE75.179.74.6 (3.5 to 5.6)71.173.01.9 (1.1 to 2.6)
ACEF vs AGEF77.777.60.1 (−0.5 to 0.7)0.66971.972.10.2 (−0.2 to 0.6)0.374
ACEF vs GRACE77.779.72.0 (0.7 to 3.1)0.00271.973.01.1 (0.2 to 2.0)0.022
AGEF vs GRACE77.679.72.1 (0.9 to 3.2)72.173.00.9 (0.0 to 1.8)0.049
BleedingC-ACS vs ACEF57.864.16.3 (2.9 to 9.8)58.057.60.4 (−1.7 to 2.4)0.744
C-ACS vs AGEF57.865.07.2 (3.9 to 10.6)58.058.20.2 (−1.8 to 2.3)0.828
C-ACS vs GRACE57.864.66.8 (4.1 to 9.6)58.059.41.4 (−0.1 to 3.0)0.062
ACEF vs AGEF64.165.00.9 (−0.5 to 2.3)0.19257.658.20.6 (−0.2 to 1.4)0.149
ACEF vs GRACE64.164.60.5 (−2.3 to 3.3)0.72457.659.41.8 (0.1 to 3.5)0.038
AGEF vs GRACE65.064.60.4 (−2.4 to 3.2)0.76558.259.41.2 (−0.5 to 2.9)0.155
ROC – receiver operating characteristics; NSTE-ACS – non-ST segment-elevation acute coronary syndrome; STEMI – ST segment elevation myocardial infarction; C-ACS – Canada Acute Coronary Syndrome risk score; ACEF – age, creatinine and ejection fraction risk score; AGEF – modified version of ACEF risk score; GRACE – Global Registry for Acute Coronary Events risk scores; MACE – major adverse clinical events.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750