Sites and Causes of Infection in Patients with Sepsis-Associated Liver Dysfunction: A Population Study from the Medical Information Mart for Intensive Care III

27 February 2021 : Database Analysis

Jinfeng Lin^1BCEF, Chunfeng Gu^2CD, Suyan Zhang^1B, Lijun Tian^1B, Ke Ren^1B, Zhilong Cao^1B, Xudong Han^1AG*

DOI: 10.12659/MSM.928928

Med Sci Monit 2021; 27:e928928

Background Material and Methods Result Discussion Conclusions References

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Table 7 Subgroup analysis of the effect of pathogen type on the occurrence of SALD.

Pathogens	Odds ratio (95% CI)	P value

Coagulase-positive	0.945 (0.838–1.064)	0.350
Coagulase-negative	1.324 (1.177–1.489)	<0.001
	1.287 (1.126–1.471)	<0.001
Methicillin-resistant	0.903 (0.713–1.144)	0.398
	0.879 (0.701–1.103)	0.265
species	0.867 (0.684–1.097)	0.235
β (group B)	0.859 (0.534–1.380)	0.529
Viridans	1.435 (1.019–2.019)	0.038
	1.305 (0.867–1.966)	0.202
	3.065 (2.344–4.008)	<0.001
	1.049 (0.708–1.556)	0.810
β	0.798 (0.486–1.31)	0.372
species	1.801 (1.235–2.627)	0.002
α	0.89 (0.518–1.527)	0.671

	1.242 (1.077–1.431)	0.003
	1.066 (0.902–1.259)	0.453
	1.292 (1.087–1.534)	0.004
	0.52 (0.348–0.777)	0.001
	1.454 (1.119–1.889)	0.005
	1.482 (1.076–2.042)	0.016
	0.557 (0.341–0.912)	0.020
	1.521 (1.126–2.054)	0.006
	2.061 (1.522–2.791)	<0.001
	2.066 (1.511–2.824)	<0.001
	1.094 (0.72–1.663)	0.674
	1.92 (1.297–2.841)	0.001
species	0.625 (0.303–1.288)	0.203

Yeast	1.606 (1.441–1.79)	<0.001
	0.485 (0.211–1.116)	0.089
	1.616 (1.328–1.967)	<0.001
	1.793 (1.255–2.563)	0.001
	2.144 (1.374–3.347)	0.001

Herpes simplex virus type 1	1.918 (1.23–2.992)	0.004
Herpes simplex virus type 2	0.65 (0.209–2.025)	0.457
SALD – sepsis-associated liver dysfunction; CI – confidence interval.

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