26 April 2021 : Clinical Research
Risk Factors for the Development of Intraoperative Hypoxia in Patients Undergoing Nonintubated Video-Assisted Thoracic Surgery: A Retrospective Study from a Single Center
Lan Lan1AE*, Yanyi Cen1BD, Long Jiang23BF, Huazhang Miao4C, Weixiang Lu23BDOI: 10.12659/MSM.928965
Med Sci Monit 2021; 27:e928965
Table 2 Intraoperative comparisons of patients with or without hypoxia.
| Variables | Before matching | After matching | ||||
|---|---|---|---|---|---|---|
| Nonhypoxia (n=2497) | Hypoxia (n=245) | P value | Nonhypoxia (n=240) | Hypoxia (n=240) | P value | |
| Surgery time, min | 80 (50, 125) | 80 (50, 135) | 0.453 | 75 (50, 130) | 80 (50, 135) | 0.306 |
| Blood loss, mL | 15 (5, 45) | 15 (10, 50) | 0.057 | 15 (5, 45) | 15 (10, 50) | 0.143 |
| Intraoperative minimum SpO, % | 98.26±1.76 | 90.68±3.05 | <0.001 | 98.32±1.78 | 90.68±3.07 | <0.001 |
| Level of intraoperative SpO, n (%) | <0.001 | <0.001 | ||||
| 94–100% | 2493 (100) | 0 | 240 (100) | 0 | ||
| 90–93% | 0 | 211 (86) | 0 | 207 (86) | ||
| ≤89% | 0 | 34 (14) | 0 | 33 (14) | ||
| Intraoperative maximum PCO, mmHg | n=197545.62±7.24 | n=17549.82±9.65 | <0.001 | n=17745.25±6.73 | n=15949.90±9.46 | <0.001 |
| Level of intraoperative PCO, n (%) | n=1975 | n=175 | n=177 | n=159 | ||
| 30–45 mmHg | 1192 (60.4) | 76 (43.4) | 107 (61) | 67 (42) | ||
| 46–60 mmHg | 724 (36.7) | 75 (42.9) | 68 (38) | 70 (44) | ||
| 61–80 mmHg | 59 (3.0) | 23 (13.1) | 2 (1) | 21 (13) | ||
| >81 mmHg | 0 | 1 (0.6) | <0.001 | 0 | 1 (1) | <0.001 |
| PCO – End-expiratory carbon dioxide partial pressure; SpO – pulse oxygen saturation. | ||||||






