10 April 2021 : Clinical Research
Clinical Application of Chromosomal Microarray Analysis in Pregnant Women with Advanced Maternal Age and Fetuses with Ultrasonographic Soft Markers
Zhu-Ming Hu1ABCE, Lei-Lei Li1ABD, Han Zhang1BF, Hong-Guo Zhang1BC, Rui-Zhi Liu1AFG, Yang Yu1ACF*DOI: 10.12659/MSM.929074
Med Sci Monit 2021; 27:e929074
Table 1 Clinical characteristics of the women compared among groups.
| Clinical characteristics | All | Group 1 | Group 2 | Group 3 | p |
|---|---|---|---|---|---|
| Number of cases | 1521 | 633 | 750 | 138 | |
| Maternal age (year) (Mean±SD) | 33.27±5.57 | 38.18±2.66 | 28.42±3.08 | 37.14±2.24 | <0.01 |
| GA at amniocentesis (days) (Means±SD) | 141.63±19.86 | 136.34±13.21 | 146.26±23.33 | 140.69±18.64 | <0.01 |
| Pregnancy outcomes | |||||
| Ongoing/LB n (%) | 1464 (96.25) | 615 (97.16) | 719 (95.87) | 130 (94.20) | >0.05 |
| TOP n (%) | 57 (3.75) | 18 (2.84) | 31 (4.13) | 8 (5.80) | >0.05 |
| SD – standard deviation; GA – gestational age; LB – live birth; TOP – termination of pregnancy. | |||||